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ALX-270-405 Revised 14-Jul-08
(E)-4-Hydroxyhexenal
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SYNONYMS 4-HHE
(E)-(±)-4-Hydroxy-2-hexenal
PRODUCT LINE Oxidative Stress
PRODUCT CATEGORY Lipid Peroxidation
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-270-405-M001   1 mg 45.00 USD Add To Cart
ALX-270-405-M005   5 mg 199.00 USD Add To Cart
ALX-270-405-M010   10 mg 354.00 USD Add To Cart
Product Specification
FORMULA: C6H10O2
MW: 114.1
CAS NUMBER: 160708-91-8
CONCENTRATION: 10mg/ml 
PURITY: ≥98%
FORMULATION: Liquid. Solution in ethanol.
SOLUBILITY: Soluble in DMSO, dimethyl formamide or acetonitrile.
SHIPPING: SHIPPED ON DRY ICE
LONG TERM STORAGE: -80°C
USE/STABILITY: Stable for at least 6 months after receipt when stored at -80°C.

Product Description
Lipid peroxidation product derived from oxidized ω-3 fatty acids such as docosahexaneoic acid.
Product Specific Literature References
4-Hydroxyhexenal: a lipid peroxidation product derived from oxidized docosahexaenoic acid: F.J. Van Kuijk, et al.; Biochim. Biophys. Acta 1043, 116 (1990) Abstract
Quantitative measurement of 4-hydroxyalkenals in oxidized low-density lipoprotein by gas chromatography-mass spectrometry: F.J. van Kuijk, et al.; Anal. Biochem. 224, 420 (1995) Abstract
Induction of endothelial iNOS by 4-hydroxyhexenal through NF-kappaB activation: J.Y. Lee, et al.; Free Radic Biol. Med. 37, 539 (2004) Abstract
NF-kappaB activation mechanism of 4-hydroxyhexenal via NIK/IKK and p38 MAPK pathway: J.H. Je, et al.; FEBS Lett. 566, 183 (2004) Abstract
Induction of endothelial apoptosis by 4-hydroxyhexenal: J.Y. Lee, et al.; Eur. J. Biochem. 271, 1339 (2004) Abstract
Specific markers of lipid peroxidation issued from n-3 and n-6 fatty acids: M. Guichardant, et al.; Biochem. Soc. Trans. 32, 139 (2004) Abstract
4-Hydroxyhexenal is a potent inducer of the mitochondrial permeability transition: B.S. Kristal, et al.; J. Biol. Chem. 271, 6033 (1996) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION To change the solvent, evaporate the ethanol under a gentle stream of nitrogen and immediately add the solvent of choice.
 
 
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