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ALX-550-066 Revised 03-Apr-08
(E)-Capsaicin
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SYNONYMS (E)-N-([4-Hydroxy-3-methoxyphenyl]methyl)-8-methyl-6-nonenamide
trans-8-Methyl-N-vanillyl-6-nonenamide
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Neurotoxins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-550-066-M100   100 mg 48.00 USD Add To Cart
Product Specification
FORMULA: C18H27NO3
MW: 305.4
CAS NUMBER: 404-86-4
MERCK INDEX: 14: 1768
RTECS: RA8530000
SOURCE/HOST: Isolated from Capsicum fruit.
PURITY: ≥98%
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in 100% ethanol, methanol or chloroform; sparingly soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HAZARD: POTENT NEUROTOXIN. IRRITANT.

Product Description
Constituent of cayenne pepper. Powerful excitant of peripheral sensory nerve endings, specifically unmyelinated afferent neurons (C-fibers). Elicits pain by activating TRPV1. Chemoprotective against some chemical carcinogens and mutagens. Reversibly inhibits aggregation of platelets.
Product Specific Literature References
Capsaicin: identification, nomenclature, and pharmacotherapy: G.A. Cordell & O.E. Araujo; Ann. Pharmacother. 27, 330 (1993), (Review) Abstract
Capsaicin, a double-edged sword: toxicity, metabolism, and chemopreventive potential: Y. J. Surh & S. S. Lee; Life Sci. 56, 1845 (1995), (Review) Abstract
Topical capsaicin. A review of its pharmacological properties and therapeutic potential in post-herpetic neuralgia, diabetic neuropathy and osteoarthritis: C. Rains & H. M. Bryson; Drugs Aging 7, 317 (1995), (Review) Abstract
Peppers and pain. The promise of capsaicin: B. M. Fusco & M. Giacovazzo; Drugs 53, 909 (1997), (Review) Abstract
Capsaicin sensitive-sensory nerves and blood pressure regulation: P. Vaishnava & D.H. Wang; Curr. Med. Chem. Cardiovasc. Hematol. Agents 1, 177 (2003), (Review) Abstract
Forty years in capsaicin research for sensory pharmacology and physiology: J. Szolcsanyi; Neuropeptides 38, 377 (2004), (Review) Abstract
Further Categories Containing This Product:
Natural Products for Neurological Research • TRPV1 Agonists and Antagonists / Related Products • Alkaloids • Active Substances from Fruit and Vegetables
 
 
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