ALEXIS Biochemicals: ETB-Receptor Agonist [4 Ala ET-1]

ALX-155-010

Revised 05-Dec-04

ETB-Receptor Agonist [4 Ala ET-1]
SYNONYMS	[Ala^1,3,11,15]-Endothelin-1
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Endothelins [ETs] & Endothelin Receptors/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-155-010-PC05		0.5 mg*	210.00 USD
ALX-155-010-P001		1 mg*	380.00 USD

Product Specification

SEQUENCE:	H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH
FORMULA:	C₁₀₉H₁₆₃N₂₅O₃₂
MW:	2335.7
QUANTITY:	*Sold as net peptide weight.
PURITY:	≥97%
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Highly selective ligand for the ET_Breceptor.

Product Specific Literature References

[Ala1,3,11,15]endothelin-1 analogs with ETB agonistic activity: T. Saeki, et al.; BBRC 179, 286 (1991) Abstract
Identification of high affinity endothelin-1 receptor subtypes in human tissues: D.L. Williams Jrs., et al.; BBRC 180, 475 (1991) Abstract
Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala1,3,11,15]ET-1: K. Nakamichi, et al.; BBRC 182, 144 (1992) Abstract
Solid-phase synthesis of [Ala1,3,11,15]-endothelin-1 by a modified double-coupling procedure: J. Green; Int. J. Pept. Prot. Res. 41, 492 (1993) Abstract

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