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ALX-350-322 Revised 20-Feb-08
Equisetin
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Antibiotics - ATPase Inhibitors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-350-322-M001   1 mg 120.00 USD Add To Cart
Product Specification
FORMULA: C22H31NO4
MW: 373.5
CAS NUMBER: 57749-43-6
SOURCE/HOST: Isolated from Fusarium equiseti.
PURITY: ≥97% (HPLC)
APPEARANCE: Brown oily solid.
SOLUBILITY: Soluble in DMSO or 100% ethanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light.
HAZARD: TOXIC.
IDENTITY: Identity determined by 1H-NMR, 13C-NMR and MS.

Product Description
Fungal metabolite with antibiotic and cytotoxic activity. Inhibitor of mitochondrial ATPases and HIV-1 integrase. Mycotoxin.
Product Specific Literature References
Antibiotic produced by Fusarium equiseti NRRL 5537: H.R. Burmeister, et al.; Antimicrob. Agents Chemother. 5, 634 (1974) Abstract
Equisetin, an antibiotic from Fusarium equiseti NRRL 5537, identified as a derivative of N-methyl-2,4-pyrollidone: R.F. Vesonder, et al.; J. Antibiot. 32, 759 (1979) Abstract
The effect of equisetin on energy-linked reactions in Rhodospirillum rubrum chromatophores: P. Nyren and A. Strid; Arch. Biochem. Biophys. 268, 659 (1989) Abstract
Characterization of the Fusarium toxin equisetin: the use of phenylboronates in structure assignment: N. J. Phillips, et al.; JACS 111, 8223 (1989)
Characterization of a mitochondrial inorganic pyrophosphatase in Saccharomyces cerevisiae: M. Lundin, et al.; Biochim. Biophys. Acta 1098, 217 (1992) Abstract
Effects of equisetin on rat liver mitochondria: evidence for inhibition of substrate anion carriers of the inner membrane: T. Konig, et al.; J. Bioenerg. Biomembr. 25, 537 (1993) Abstract
Equisetin and a novel opposite stereochemical homolog phomasetin, two fungal metabolites as inhibitors of HIV-1 integrase: S.B. Singh, et al.; Tetrahedron Lett. 39, 2243 (1998)
Isolation and characterization of novel human immunodeficiency virus integrase inhibitors from fungal metabolites: D. Hazuda, et al.; Antivir. Chem. Chemother. 10, 63 (1999) Abstract
Phytotoxicity of equisetin and epi-equisetin isolated from Fusarium equiseti and F. pallidoroseum: M.H. Wheeler, et al.; Mycological Res. 103, 967 (1999)
A short stereoselective total synthesis of the fusarium toxin equisetin: L.T. Burke, et al.; Org. Lett. 2, 3611 (2000) Abstract
Enantioselective total synthesis of (−)-equisetin using a Me3Al-mediated intramolecular Diels–Alder reaction: K. Yuki, et al.; Tetrahedron Lett. 427, 2517 (2001)
Natural products with anti-HIV activity from marine organisms: L.A. Tziveleka, et al.; Curr. Top. Med. Chem. 3, 1512 (2003) Abstract
Total synthesis of the Fusarium toxin equisetin: L.T. Burke, et al.; Org. Biomol. Chem. 3, 274 (2005) Abstract
Equisetin biosynthesis in Fusarium heterosporum: J.W. Sims; Chem. Commun. 2005, 186
Molecular biology of Fusarium mycotoxins: A.E. Desjardins & R.H. Proctor; Int. J. Food Microbiol. 119, 47 (2007) Abstract
Further Categories Containing This Product:
HIV / AIDS / Related ProductsMycotoxins
 
 

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