ALEXIS Biochemicals: Esculin . hydrate

ALX-350-021

Revised 05-Apr-08

Esculin . hydrate
SYNONYMS	6,7-Dihydroxycoumarin 6-glucoside
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Natural Products - Antioxidants

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-021-G005		5 g	25.00 USD

Product Specification

FORMULA:	C₁₅H₁₆O₉ . H₂O
MW:	340.3 . 18.0
CAS NUMBER:	531-75-9
MERCK INDEX:	14: 3698
RTECS:	DJ3085000
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in methanol (50mg/ml).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Antioxidant used as a skin protectant. Shows vitamin P activity. Protects cells against DNA damage. Reduces ROS levels. Inhibits carcinogenesis.

Product Specific Literature References

HPLC Analysis of Esculin and Fraxin in Horse-Chestnut Bark (Aesculus hippocastanum L.): G. Stanic, et al.; Croatica Chemica Acta 72, 827 (1999) Full Text
Suppression of lipid hydroperoxide-induced oxidative damage to cellular DNA by esculetin: T. Kaneko, et al.; Biol. Pharm. Bull. 26, 840 (2003) Abstract
Effects of esculin and esculetin on the survival of Escherichia coli O157 in human faecal slurries, continuous-flow simulations of the rumen and colon and in calves: S.H. Duncan, et al.; Br. J. Nutr. 91, 749 (2004) Abstract
Inhibitory effect of esculin on oxidative DNA damage and carcinogenesis induced by N-nitrosobis(2-oxopropyl)amine in hamster pancreas: T. Kaneko, et al.; Biofactors 22, 83 (2004) Abstract
Anti-apoptotic effect of esculin on dopamine-induced cytotoxicity in the human neuroblastoma SH-SY5Y cell line: D.L. Zhao, et al.; Neuropharmacology 53, 724 (2007) Abstract

Further Categories Containing This Product:

Natural Products - Antitumor Reagents • Free Radical Scavengers • Natural Products - Apoptosis Inducers & Inhibitors

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