ALEXIS Biochemicals: FPL 64176

ALX-550-229

Revised 11-Nov-05

FPL 64176
SYNONYMS	2,5-Dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylic acid methyl ester
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Ca2+ Channels (L-type)

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-550-229-M005		5 mg	70.00 USD

Product Specification

FORMULA:	C₂₂H₂₁NO₃
MW:	347.4
CAS NUMBER:	120934-96-5
PURITY:	≥99%
APPEARANCE:	White to tan powder.
SOLUBILITY:	Soluble in 100% ethanol or DMSO; insoluble in aqueous solution.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C
HANDLING:	Hygroscopic. Protect from light.

Product Description

Potent Ca²⁺channel (L-type) activator.

Product Specific Literature References

A new site for the activation of cardiac calcium channels defined by the nondihydropyridine FPL 64176: D. Rampe & A.E. Lacerda; J. Pharmacol. Exp. Ther. 259, 982 (1991) Abstract
Pharmacological, radioligand binding, and electrophysiological characteristics of FPL 64176, a novel nondihydropyridine Ca2+ channel activator, in cardiac and vascular preparations: W. Zheng, et al.; Mol. Pharmacol. 40, 734 (1991) Abstract
Comparison of the in vitro and in vivo cardiovascular effects of two structurally distinct Ca++ channel activators, BAY K 8644 and FPL 64176: D. Rampe, et al.; J. Pharmacol. Exp. Ther. 265, 1125 (1993) Abstract

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