ALEXIS Biochemicals: FURA 2/AM

ALX-620-005

Revised 22-Feb-08

FURA 2/AM
SYNONYMS	1-[2-(5-Carboxyoxazol-2-yl)-6-aminobenzofuran-5-oxy]-2-(2'-amino-5'-methyl-phenoxy)ethane-N,N,N',N'-tetraacetic acid, pentaacetoxymethyl ester
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Calcium Chelators / Caged Calcium Chelators

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-620-005-M001		1 mg	135.00 USD

Product Specification

FORMULA:	C₄₄H₄₇N₃O₂₄
MW:	1001.9
CAS NUMBER:	108964-32-5
PURITY:	≥98% (HPLC)
APPEARANCE:	Off-white to yellow solid.
SOLUBILITY:	Soluble in acetonitrile or DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light and moisture.
IDENTITY:	Determined by ¹H-NMR and fluorescence.

Product Description

Cell permeable analog of FURA 2 (Prod. No. ALX-620-004). Fluorescent probe for Ca²⁺. After crossing the membrane, the product is quickly metabolized by cytoplasmic esterases to the membrane impermeant FURA 2.

Product Specific Literature References

Fura-2 measurement of cytosolic free Ca2+ in monolayers and suspensions of various types of animal cells: A. Malgaroli, et al.; J. Cell. Biol. 105, 2145 (1987) Abstract
A Ca2+-insensitive form of fura-2 associated with polymorphonuclear leukocytes. Assessment and accurate Ca2+ measurement: M. Scanlon, et al.; J. Biol. Chem. 262, 6308 (1987) Abstract; Full Text
Intracellular calibration of the fluorescent calcium indicator Fura-2: D.A. Williams & F.S. Fay; Cell Calcium 11, 75 (1990) Abstract
Stretch-induced increases in intracellular calcium of isolated vascular smooth muscle cells: M.J. Davis, et al.; Am. J. Physiol. 263, H1292 (1992) Abstract
Positive and negative inotropic effects of phorbol 12-myristate 13- acetate: relationship to PKC-dependence and changes in [Ca2+]i: C.A. Ward & M.P. Moffat; J. Mol. Cell. Cardiol. 24, 937 (1992) Abstract

Further Categories Containing This Product:

Calcium Indicators / Probes • MDR Other Products • Dyes / Stains / Fluorescent Probes / Fluorescent Labels

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