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Cell Death / Apoptosis / Autophagy
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ALX-307-021 Revised 20-Feb-08
3-Deoxy-3-fluoro-D-myo-inositol 1,4,5-trisphosphate . hexasodium salt
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SYNONYMS 3-F-Deoxy-Ins(1,4,5)P3 . 6Na
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-021-C100   100 µg 40.00 USD Add To Cart
Product Specification
FORMULA: C6H8FO14P3 . 6Na
MW: 416.0 . 137.9
CAS NUMBER: 129365-68-0
PURITY: ≥99%
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.

Product Description
Equipotent to Ins(1,4,5)P3 in releasing intracellular calcium. The 3-position is blocked by fluorine, hence it cannot be converted to Ins(1,3,4,5)P4 by the action of 3-kinases. It may therefore provide a useful tool for studying the complex biochemical pathways in which InsP3 and InsP4 are closely interactive.
Product Specific Literature References
Synthesis of the First Optically Pure, Fluorinated Inositol 1,4,5-Trisphosphate of myo-Inositol Stereochemistry and Its Effect on Ca2+  Release in Swiss 3T3 Cells: A.P. Kozikowski, et al.; JACS 112, 7403 (1990)
 
 
ALX-307-026 Revised 28-Nov-08
D-myo-Inositol 1-monophosphate . dipotassium salt
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SYNONYMS Ins(1)P1 . 2K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
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ALX-307-026-M001   1 mg 63.00 USD Add To Cart
ALX-307-026-M005   5 mg 158.00 USD Add To Cart
Product Specification
FORMULA: C6H11O9P . 2K
MW: 258.1 . 78.2
CAS NUMBER: 573-35-3
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light and moisture. Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

 
 
ALX-307-027 Revised 28-Nov-08
DL-myo-Inositol 1,5-bisphosphate . dipotassium salt
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SYNONYMS DL-Ins(1,5)P2 . 2K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
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ALX-307-027-C100   100 µg 60.00 USD Add To Cart
ALX-307-027-M001   1 mg 280.00 USD Add To Cart
Product Specification
FORMULA: C6H12O12P2 . 2K
MW: 338.1 . 78.2
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

 
 
ALX-307-028 Revised 28-Nov-08
D-myo-Inositol 1,5-bisphosphate . tetrapotassium salt
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SYNONYMS Ins(1,5)P2 . 4K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-028-C100   100 µg 60.00 USD Add To Cart
ALX-307-028-M001   1 mg 280.00 USD Add To Cart
Product Specification
FORMULA: C6H10O12P2 . 4K
MW: 336.1 . 156.4
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

 
 
ALX-307-029 Revised 28-Nov-08
D-myo-Inositol 1,4,6-trisphosphate . tripotassium salt
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SYNONYMS Ins(1,4,6)P3 . 3K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
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ALX-307-029-C100   100 µg 70.00 USD Add To Cart
ALX-307-029-M001   1 mg 320.00 USD Add To Cart
Product Specification
FORMULA: C6H12O15P3 . 3K
MW: 417.1 . 117.3
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

 
 
ALX-307-030 Revised 28-Nov-08
D-myo-Inositol 2,3,5-trisphosphate . tripotassium salt
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SYNONYMS Ins(2,3,5)P3 . 3K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
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ALX-307-030-C100   100 µg 70.00 USD Add To Cart
ALX-307-030-M001   1 mg 320.00 USD Add To Cart
Product Specification
FORMULA: C6H12O15P3 . 3K
MW: 417.1 . 117.3
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

 
 
ALX-307-031 Revised 28-Nov-08
D-myo-Inositol 1,2,3,5-tetrakisphosphate . tetrapotassium salt
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SYNONYMS Ins(1,2,3,5)P4 . 4K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
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ALX-307-031-C100   100 µg 110.00 USD Add To Cart
Product Specification
FORMULA: C6H12O18P4 . 4K
MW: 496.1 . 156.4
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

 
 
ALX-307-032 Revised 28-Nov-08
DL-myo-Inositol 1,3,4,5-tetrakisphosphate . tetrapotassium salt
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SYNONYMS DL-Ins(1,3,4,5)P4 . 4K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
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ALX-307-032-C100   100 µg 110.00 USD Add To Cart
Product Specification
FORMULA: C6H12O18P4 . 4K
MW: 496.1 . 156.4
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

 
 
ALX-307-033 Revised 28-Nov-08
DL-myo-Inositol 1,4,5,6-tetrakisphosphate . tetrapotassium salt
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SYNONYMS DL-Ins(1,4,5,6)P4 . 4K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
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ALX-307-033-C100   100 µg 110.00 USD Add To Cart
Product Specification
FORMULA: C6H12O18P4 . 4K
MW: 496.1 . 156.4
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

 
 
ALX-307-034 Revised 28-Nov-08
D-myo-Inositol 1,4,5,6-tetrakisphosphate . tetrapotassium salt
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SYNONYMS Ins(1,4,5,6)P4 . 4K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
Ordering Information
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ALX-307-034-C100   100 µg 110.00 USD Add To Cart
Product Specification
FORMULA: C6H12O18P4 . 4K
MW: 496.1 . 156.4
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

Product Description
For the cell permeable PM-derivative, see Prod. No. ALX-307-060.
Product Specific Literature References
D-myo-Inositol 1,4,5,6-tetrakisphosphate produced in human intestinal epithelial cells in response to Salmonella invasion inhibits phosphoinositide 3-kinase signaling pathways: L. Eckmann, et al.; PNAS 94, 14456 (1997) Abstract
Enzyme-assisted total synthesis of the optical antipodes D-myo-inositol 3,4,5-trisphosphate and D-myo-inositol 1,5, 6-trisphosphate: aspects of their structure-activity relationship to biologically active inositol phosphates: S. Adelt, et al.; J. Med. Chem. 42, 1262 (1999) Abstract
 
 
ALX-307-036 Revised 28-Nov-08
D-myo-Inositol 1,3,5,6-tetrakisphosphate . tetrapotassium salt
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SYNONYMS Ins(1,3,5,6)P4 . 4K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
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ALX-307-036-C100   100 µg 110.00 USD Add To Cart
Product Specification
FORMULA: C6H12O18P4 . 4K
MW: 496.1 . 156.4
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

 
 
ALX-307-037 Revised 28-Nov-08
D-myo-Inositol 1,3,4,5,6-pentakisphosphate . pentapotassium salt
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SYNONYMS Ins(1,3,4,5,6)P5 . 5K
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
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ALX-307-037-C100   100 µg 45.00 USD Add To Cart
ALX-307-037-M001   1 mg 380.00 USD Add To Cart
Product Specification
FORMULA: C6H12O21P5 . 5K
MW: 575.0 . 195.5
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Hygroscopic.
IDENTITY: Identity determined by 1H-NMR, 31P-NMR and MS.

Product Specific Literature References
Synthesis of myo-inositol 1,3,4,5,6-pentakisphosphate from inositol phosphates generated by receptor activation: L.R. Stephens, et al.; Biochem. J. 253, 721 (1988) Abstract
Inositol 1,3,4,5,6-pentakisphosphate and inositol hexakisphosphate are inhibitors of the soluble inositol 1,3,4,5-tetrakisphosphate 3-phosphatase and the inositol 1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase from pig brai: A. Höer & E. Oberdisse; Biochem. J. 278, 219 (1991) Abstract
Mutation of the pleckstrin homology domain of Bruton's tyrosine kinase in immunodeficiency impaired inositol 1,3,4,5-tetrakisphosphate binding capacity: M. Fukuda, et al.; J. Biol. Chem. 271, 30303 (1996) Abstract; Full Text
 
 
ALX-307-038 Revised 28-Nov-08
D-myo-Inositol 3,4-bisphosphate, L-α-Phosphatidyl-(1,2-dipalmitoyl)-
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SYNONYMS PtdIns(3,4)P2, (1,2-dipalmitoyl)-
L-α-Phosphatidyl-(1,2-dipalmitoyl)-D-myo-inositol 3,4-bisphosphate
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Inositols & Inositolphosphates / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-307-038-C100   100 µg