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Obesity & Adipokines
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ALX-350-163 Revised 15-Sep-08 New product
Agistatine D
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Other Natural Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-350-163-M001   1 mg 90.00 USD Add To Cart
ALX-350-163-M005   5 mg 360.00 USD Add To Cart
Product Specification
FORMULA: C11H14O4
MW: 210.2
CAS NUMBER: 144096-47-9
SOURCE/HOST: Isolated from fungus FH-A 6239.
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in DMSO or acetone.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
IDENTITY: Identity determined by 1H-NMR.

Product Description
Analog of agistatine A, which has been described as an inhibitor of cholesterol biosynthesis.
Product Specific Literature References
Secondary Metabolites by Chemical Screening, 29: A. Zeeck, et al.; Liebigs Ann. 1996, 627
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Further Categories Containing This Product:
Cholesterol & Lipid Transport / Related Products
 
 
ALX-350-160 Revised 03-Sep-08 New product
Aloeresin A
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Other Natural Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-350-160-M001   1 mg 185.00 USD Add To Cart
Product Specification
FORMULA: C28H28O11
MW: 540.5
CAS NUMBER: 74545-79-2
SOURCE/HOST: Isolated from Aloe sp.
PURITY: ≥97% (HPLC)
APPEARANCE: Brown solid.
SOLUBILITY: Soluble in DMSO or 100% ethanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light.
IDENTITY: Identity determined by 1H-NMR and MS.

Product Description
Metabolite of aloesin (Prod. No. ALX-350-158).  Inhibits α-glucosidases.
Product Specific Literature References
Metabolism of aloesin and related compounds by human intestinal bacteria: a bacterial cleavage of the C-glucosyl bond and the subsequent reduction of the acetonyl side chain: Q.M. Che, et al.; Chem. Pharm. Bull. (Tokyo) 39, 704 (1991) Abstract
Geographical variation in the major compounds of Aloe ferox leaf exudate: B.E. van Wyk, et al.; Planta Med. 61, 250 (1995) Abstract
High-performance liquid chromatographic profiles of aloe constituents and determination of aloin in beverages, with reference to the EEC regulation for flavouring substances: F. Zonta, et al.; J. Chromatogr. A. 718, 99 (1995) Abstract
Determination of aloesin and aloeresin A for the detection of aloe in beverages: M. Dell’Agli, et al.; J. Agric. Food Chem. 55, 3363 (2007) Abstract
A reversed-phase high-performance liquid chromatographic method for the determination of aloesin, aloeresin A and anthraquinone in Aloe ferox: M. Zahn, et al.; Phytochem. Anal. 19, 122 (2008) Abstract
alpha-Glucosidase inhibitor from Chinese aloes: N. Jong-Anurakkun, et al.; Fitoterapia 79, 456 (2008) Abstract
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Further Categories Containing This Product:
Glycosidases / Related Products
 
 
ALX-201-431 Revised 06-Aug-08 New product
ANGPTL4 (Intact Form) (human) (recombinant) (His)
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SYNONYMS Angiopoietin-like Protein 4 (Intact Form) (human) (recombinant) (His)
FIAF (Intact Form) (human) (recombinant) (His)
Fasting-induced Adipose Factor (Intact Form) (human) (recombinant) (His)
HFARP (Intact Form) (human) (recombinant) (His)
Hepatic Fibrinogen/Angiopoietin-related Protein (Intact Form) (human) (recombinant) (His)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs] / Related Products
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ALX-201-431-C010   10 µg 320.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in CHO cells. The signal peptide and the mature peptide of human ANGPTL4 (aa 1-406) are fused at the C-terminus to a His-tag.
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2μm-filtered solution in PBS.
ENDOTOXIN CONTENT: <1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q9BY76: ANGPTL4 (human)
MANUFACTURER Manufactured by AdipoGen, Inc.
General Literature References
Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation: J.C. Yoon, et al.; Mol. Cell Biol. 20, 5342 (2000) Abstract; Full Text
Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene: S. Kersten, et al.; J. Biol. Chem. 275, 28488 (2000) Abstract; Full Text
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice: A. Xu, et al.; PNAS 102, 6086 (2005) Abstract; Full Text
Genes that mediate breast cancer metastasis to lung: A.J. Minn, et al.; Nature 436, 518 (2005) Abstract; Full Text
Angiopoietin-like-4 is a potential angiogenic mediator in arthritis: L.M. Hermann, et al.; Clin. Immunol. 115, 93 (2005) Abstract
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Recombinant Proteins / Fusion Proteins
 
 
ALX-201-432 Revised 12-Aug-08 New product
ANGPTL4 (Intact Form) (rat) (recombinant) (His)
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SYNONYMS Angiopoietin-like Protein 4 (Intact Form) (rat) (recombinant) (His)
FIAF (Intact Form) (rat) (recombinant) (His)
Fasting-induced Adipose Factor (Intact Form) (rat) (recombinant) (His)
HFARP (Intact Form) (rat) (recombinant) (His)
Hepatic Fibrinogen/Angiopoietin-related Protein (Intact Form) (rat) (recombinant) (His)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs] / Related Products
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ALX-201-432-C010   10 µg 300.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in CHO cells. The signal peptide and the mature peptide of rat ANGPTL4 (aa 1-405) are fused at the C-terminus to a His-tag.
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2μm-filtered solution in PBS.
ENDOTOXIN CONTENT: <1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
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General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q6TMA8: ANGPTL4 (rat)
MANUFACTURER Manufactured by AdipoGen, Inc.
General Literature References
Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation: J.C. Yoon, et al.; Mol. Cell Biol. 20, 5342 (2000) Abstract; Full Text
Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene: S. Kersten, et al.; J. Biol. Chem. 275, 28488 (2000) Abstract; Full Text
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice: A. Xu, et al.; PNAS 102, 6086 (2005) Abstract; Full Text
Genes that mediate breast cancer metastasis to lung: A.J. Minn, et al.; Nature 436, 518 (2005) Abstract; Full Text
Angiopoietin-like-4 is a potential angiogenic mediator in arthritis: L.M. Hermann, et al.; Clin. Immunol. 115, 93 (2005) Abstract
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Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
 
 
ALX-201-424 Revised 09-Jun-08 New product
ANGPTL4 (Fibrinogen-like Domain) (mouse) (recombinant)
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SYNONYMS Angiopoietin-like Protein 4 (Fibrinogen-like Domain) (mouse) (recombinant)
FIAF (Fibrinogen-like Domain) (mouse) (recombinant)
Fasting-induced Adipose Factor (Fibrinogen-like Domain) (mouse) (recombinant)
HFARP (Fibrinogen-like Domain) (mouse) (recombinant)
Hepatic Fibrinogen/Angiopoietin-related Protein (Fibrinogen-like Domain) (mouse) (recombinant)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs] / Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-424-C010   10 µg 250.00 USD Add To Cart
ALX-201-424-C050   50 µg 660.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. Fibrinogen-like domain of mouse ANGPTL4 (angiopoietin-like protein 4) (aa 167-410) is fused at the N-terminus to a FLAG®-tag.
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
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General Information
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link Q9Z1P8: Angiopoietin-related protein 4 (mouse) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by AdipoGen, Inc.
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Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
 
 
APO-54N-040 Revised 30-Sep-08 New product
Chemerin (human) Detection Set [For ELISA Application]
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SYNONYMS RARRES2 (human) Detection Set [For ELISA Application]
Retinoic Acid Receptor Responder Protein 2 (human) Detection Set [For ELISA Application]
TIG2 (human) Detection Set [For ELISA Application]
Tazarotene-induced Gene 2 (human) Detection Set [For ELISA Application]
RAR-responsive Protein (human) Detection Set [For ELISA Application]
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Adipokines Other Products
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APO-54N-040-KI01   1 Set 630.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY: 0.1ng/ml (range 0.156 to 10ng/ml).
QUANTITY: For 5x96 wells.
KIT/SET CONTAINS: 1 vial Standard (lyophilized) (STD).
1 vial Coating Antibody (COAT).
1 vial Detection Antibody (DET).
APPLICATION: For the quantitative determination of human chemerin from biological fluids (serum, plasma and cell culture supernatant).
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
General Information
Chemerin (tazarotene-induced gene 2; TIG2) is a chemotactic agent that was identified as the ligand for the orphan G protein-coupled receptor ChemR23. Recently, chemerin has been shown to be expressed abundantly in adipose tissue and to function as a new adipokine [1, 2]. Chemerin potentiates insulin-stimulated glucose uptake and regulates adipogenesis and adipocyte metabolism [1].
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
[1] Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism: K.B. Goralski, et al.; J. Biol. Chem. 282, 28175 (2007) Abstract; Full Text
[2] Chemerin is a novel adipokine associated with obesity and metabolic syndrome: K. Bozaoglu, et al.; Endocrinology 148, 4687 (2007) Abstract
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Further Categories Containing This Product:
ELISA Sets
 
 
ALX-522-142 Revised 26-Sep-08 New product
Chemerin (human) (recombinant)
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SYNONYMS RARRES2 (human) (recombinant)
Retinoic Acid Receptor Responder Protein 2 (human) (recombinant)
TIG2 (human) (recombinant)
Tazarotene-induced Gene 2 Protein (human) (recombinant)
RAR-responsive Protein (human) (recombinant)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Adipokines Other Products
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ALX-522-142-C010   10 µg 390.00 USD Add To Cart
Product Specification
MW: ~20kDa
SOURCE/HOST: Produced in HEK 293 cells. The extracellular domain of human chemerin (aa 21-157) is fused at the N-terminus to a FLAG®-tag.
CONCENTRATION: 0.1mg/ml after reconstitution.
PURITY: ≥95% (SDS-PAGE)
FORMULATION: Lyophilized. Contains PBS.
ENDOTOXIN CONTENT: <0.1EU/µg purified protein (LAL test; Lonza).
RECONSTITUTION: Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months after receipt when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q99969: RARR2 (human)

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by Apotech Corporation.
Related Products
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
 
 
ALX-380-133 Revised 20-Nov-08 New product
Decarestrictine D