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AG-CC06H2
Revised 11-Jan-08
Clusterin (human) Competitive ELISA Kit
SYNONYMS
TRPM-2 (human) Competitive ELISA Kit
Apolipoprotein J (human) Competitive ELISA Kit
APO-J (human) Competitive ELISA Kit
CLI (human) Competitive ELISA Kit
CLU (human) Competitive ELISA Kit
SGP-2 (human) Competitive ELISA Kit
PRODUCT LINE
Cell Cycle
PRODUCT CATEGORY
Clusterin / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
AG-CC06H2EK-KI01
96 wells
550.00 USD
AG-CC06H2TP-KI01
Twin Plex
2x96 wells
890.00 USD
AG-CC06H2PP-KI01
Penta Plex
5x96 wells
1'870.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY:
1ng/ml
APPLICATION:
For the quantitative determination of clusterin in human serum, plasma or cell culture supernatant.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
General Information
MANUFACTURER
Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
ELISA & EIA Kits
AG-P0731
Revised 05-Jan-09
Progranulin (human) ELISA Kit
SYNONYMS
Proepithelin (human) ELISA Kit
PEPI (human) ELISA Kit
PC Cell-derived Growth Factor (human) ELISA Kit
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
Progranulin / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
AG-P0731EK-KI01
96 wells
640.00 USD
AG-P0731TP-KI01
Twin Plex
2x96 wells
940.00 USD
AG-P0731PP-KI01
Penta Plex
5x96 wells
1'880.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY:
32pg/ml (range 0 to 8ng/ml)
SPECIFICITY:
Does not cross-react with mouse and rat progranulin.
APPLICATION:
For the quantitative determination of progranulin in human serum, plasma or cell culture supernatant.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
Product Specific Literature References
Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration:
R. Ghidoni, et al.; Neurology
71
, 1235 (2008)
Abstract
Serum Progranulin Concentrations May be Associated with Macrophage Infiltration into Omental Adipose Tissue:
B.S. Youn, et al.; Diabetes
Epub ahead of print
, (2009)
Abstract
General Information
Progranulin (PGRN) has been shown to be a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signalling cascades that control cell cycle progression and cell motility. PGRN has also been linked to tumorigenesis. The function of PGRN in the central nervous system (CNS) is also of interest, because mutations in the PGRN gene have been identified in cases of frontotemporal degeneration (FTD).
MANUFACTURER
Manufactured by AdipoGen, Inc.
General Literature References
Granulins, a novel class of peptide from leukocytes:
A. Bateman, et al.; BBRC
173
, 1161 (1990)
Abstract
Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis:
Z. He & A. Bateman; J. Mol. Med.
81
, 600 (2003)
Abstract
Progranulin is a mediator of the wound response:
Z. He, et al.; Nat. Med.
9
, 225 (2003)
Abstract
Progranulin in frontotemporal lobar degeneration and neuroinflammation:
Z. Ahmed, et al.; J. Neuroinflammation
4
, 7 (2007), (Review)
Abstract
;
Full Text
Progranulin: normal function and role in neurodegeneration:
J. L. Eriksen & I.R. Mackenzie; J. Neurochem.
104
, 287 (2008), (Review)
Abstract
Related Products
ALX-804-737
Monoclonal Antibody to Progranulin (human) (PG359-7)
ALX-201-389
Progranulin (mouse) (recombinant)
ALX-201-377
Progranulin (human) (recombinant)
AG-PM0731
Progranulin (mouse) ELISA Kit
Further Categories Containing This Product:
Inflammation Other Products
•
ELISA & EIA Kits
AG-PM0731
Revised 23-Apr-08
Progranulin (mouse) ELISA Kit
SYNONYMS
Proepithelin (mouse) ELISA Kit
PEPI (mouse) ELISA Kit
PC Cell-derived Growth Factor (mouse) ELISA Kit
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
Progranulin / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
AG-PM0731EK-KI01
96 wells
645.00 USD
AG-PM0731TP-KI01
Twin Plex
2x96 wells
945.00 USD
AG-PM0731PP-KI01
Penta Plex
5x96 wells
1'885.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SENSITIVITY:
60pg/ml (range 0 to 16 ng/ml)
SPECIFICITY:
Does not cross-react with human and rat progranulin
APPLICATION:
For the quantitative determination of progranulin in mouse serum or cell culture supernatants.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
General Information
Progranulin (PGRN) has been shown to be a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signalling cascades that control cell cycle progression and cell motility. PGRN has also been linked to tumorigenesis. The function of PGRN in the central nervous system (CNS) is also of interest, because mutations in the PGRN gene have been identified in cases of frontotemporal degeneration (FTD).
MANUFACTURER
Manufactured by AdipoGen, Inc.
General Literature References
Granulins, a novel class of peptide from leukocytes:
A. Bateman, et al.; BBRC
173
, 1161 (1990)
Abstract
Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis:
Z. He & A. Bateman; J. Mol. Med.
81
, 600 (2003)
Abstract
Progranulin is a mediator of the wound response:
Z. He, et al.; Nat. Med.
9
, 225 (2003)
Abstract
Progranulin in frontotemporal lobar degeneration and neuroinflammation:
Z. Ahmed, et al.; J. Neuroinflammation
4
, 7 (2007), (Review)
Abstract
;
Full Text
Progranulin: normal function and role in neurodegeneration:
J.L. Eriksen & I.R. Mackenzie; J. Neurochem.
104
, 287 (2008), (Review)
Abstract
Related Products
ALX-804-737
Monoclonal Antibody to Progranulin (human) (PG359-7)
AG-P0731
Progranulin (human) ELISA Kit
ALX-201-389
Progranulin (mouse) (recombinant)
ALX-201-377
Progranulin (human) (recombinant)
Further Categories Containing This Product:
Inflammation Other Products
•
ELISA & EIA Kits
ALX-101-010
Revised 11-Sep-07
L-Aspartic acid
SYNONYMS
H-L-Asp-OH
PRODUCT LINE
Combinatorial Chemistry
PRODUCT CATEGORY
L-Amino Acids
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-101-010-G001
1 g
12.00 USD
Product Specification
FORMULA:
C
4
H
7
NO
4
MW:
133.1
CAS NUMBER:
56-84-8
MERCK INDEX:
14:
840
RTECS:
CI9098500
PURITY:
≥99.5%
APPEARANCE:
White powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+20°C
Further Categories Containing This Product:
Excitatory Amino Acids
•
NMDA Receptors / Related Products
ALX-101-011
Revised 22-Nov-06
D-Aspartic acid
SYNONYMS
H-D-Asp-OH
PRODUCT LINE
Combinatorial Chemistry
PRODUCT CATEGORY
D-Amino Acids
Ordering Information
Product Numbers:
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ALX-101-011-G001
1 g
12.00 USD
Product Specification
FORMULA:
C
4
H
7
NO
4
MW:
133.1
CAS NUMBER:
1783-96-6
MERCK INDEX:
14:
840
RTECS:
CI9097500
PURITY:
≥99%
APPEARANCE:
White powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+20°C
Further Categories Containing This Product:
Excitatory Amino Acids
•
NMDA Receptors / Related Products
ALX-101-016
Revised 22-Nov-06
L-Glutamine
SYNONYMS
H-L-Gln-OH
PRODUCT LINE
Combinatorial Chemistry
PRODUCT CATEGORY
L-Amino Acids
Ordering Information
Product Numbers:
Format:
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Add To Cart
ALX-101-016-G005
5 g
12.00 USD
Product Specification
FORMULA:
C
5
H
10
N
2
O
3
MW:
146.2
CAS NUMBER:
56-85-9
MERCK INDEX:
14:
4471
RTECS:
MA2275100
PURITY:
≥98%
APPEARANCE:
White powder.
SOLUBILITY:
Soluble in water or dilute aqueous acid.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+20°C
Further Categories Containing This Product:
Excitatory Amino Acids
ALX-101-017
Revised 24-Jun-08
D-Glutamine
SYNONYMS
H-D-Gln-OH
PRODUCT LINE
Combinatorial Chemistry
PRODUCT CATEGORY
D-Amino Acids
Ordering Information
Product Numbers:
Format:
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Add To Cart
ALX-101-017-G001
1 g
32.00 USD
Product Specification
FORMULA:
C
5
H
10
N
2
O
3
MW:
146.2
CAS NUMBER:
5959-95-5
PURITY:
≥98% (TLC)
APPEARANCE:
White to off-white powder.
SOLUBILITY:
Soluble in water (50mg/ml) or dilute aqueous acid.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+20°C
IDENTITY:
Identity determined by IR.
Further Categories Containing This Product:
Excitatory Amino Acids
ALX-101-018
Revised 30-Jan-06
L-Glutamic acid
PRODUCT LINE
Combinatorial Chemistry
PRODUCT CATEGORY
L-Amino Acids
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-101-018-G001
1 g
12.00 USD
Product Specification
FORMULA:
C
5
H
9
NO
4
MW:
147.1
CAS NUMBER:
56-86-0
MERCK INDEX:
14:
4469
RTECS:
LZ9700000
PURITY:
≥99%
APPEARANCE:
White to off-white solid.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+20°C
Further Categories Containing This Product:
Excitatory Amino Acids
•
Nitric Oxide Pathway Other Products
ALX-105-009
Revised 06-Jun-06
N-Methyl-D-aspartic acid
SYNONYMS
NMDA
PRODUCT LINE
Nitric Oxide Pathway
PRODUCT CATEGORY
NOS Inhibitors (NOS Induction & Enzyme Activity)
Ordering Information
Product Numbers:
Format:
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Unit Price:
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ALX-105-009-M010
10 mg
23.00 USD
ALX-105-009-M050
50 mg
60.00 USD
Product Specification
FORMULA:
C
5
H
9
NO
4
MW:
147.1
CAS NUMBER:
6384-92-5
MERCK INDEX:
14:
6662
RTECS:
CI9457000
PURITY:
≥98%
APPEARANCE:
White crystalline powder.
SOLUBILITY:
Soluble in dilute aqueous base; slightly soluble in water or 100% ethanol.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+20°C
HANDLING:
Protect from light.
Product Description
Selective ionotropic NMDA receptor agonist.
Product Specific Literature References
Excitatory amino acid transmitters:
J.C. Watkins & R.H. Evans; Ann. Rev. Pharmacol. Toxicol.
21
, 165 (1981), (Review)
Abstract
NMDA receptors and ligands in the vertebrate CNS:
T.W. Stone & N.R. Burton; Progr. Neurobiol.
30
, 333 (1988), (Review)
Abstract
Further Categories Containing This Product:
Special Amino Acids
•
NMDA Receptors / Related Products
ALX-106-023
Revised 13-Dec-02
5-Hydroxy-L-tryptophan
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
Serotonergics & Serotonin Receptors / Related Products
Ordering Information
Product Numbers:
Format:
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ALX-106-023-M500
500 mg
20.00 USD
Product Specification
FORMULA:
C
11
H
12
N
2
O
3
MW:
220.2
CAS NUMBER:
56-69-9
APPEARANCE:
White solid.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Protect from light.
Product Description
Serotonin precursor.
Further Categories Containing This Product:
Special Amino Acids
•
Glutamate Receptors (Metabotropic) / Related Products
ALX-106-024
Revised 14-Oct-08
O-Phospho-L-serine
SYNONYMS
L-Phosphoserine
L-Serine-O-phosphate
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
NMDA Receptors / Related Products
Ordering Information
Product Numbers:
Format:
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ALX-106-024-G001
1 g
10.00 USD
Product Specification
FORMULA:
C
3
H
8
NO
6
P
