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Mycotoxins
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ALX-630-117 Revised 07-Oct-08 New product
Territrem B
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-630-117-MC05   0.5 mg 145.00 USD Add To Cart
ALX-630-117-M001   1 mg 260.00 USD Add To Cart
Product Specification
FORMULA: C29H34O9
MW: 526.6
CAS NUMBER: 70407-20-4
RTECS: QL6284000
SOURCE/HOST: Isolated from Aspergillus terreus.
PURITY: ≥95% (HPLC)
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in methanol; insoluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C

Product Description

Tremorgenic mycotoxin. Potent and specific, noncovalent yet irreversible inhibitor of acetylcholinesterase (IC50=8nM).
Product Specific Literature References
Territrems, tremorgenic mycotoxins of Aspergillus terreus: K.H. Ling, et al.; Appl. Environ. Microbiol. 37, 355 (1979) Abstract; Full Text
Biosynthesis of Territrems by Aspergillus terreus: K.H Ling & Y.W. Peng; Appl. Environ. Microbiol. 54, 585 (1988) Abstract; Full Text
Effects of territrem-B on cholinergic responses of snail neuron: V.L. Arvanov, et al.; Neurosci. Lett. 152, 69 (1993) Abstract
Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp. FO-4259. I. Screening, taxonomy, fermentation, isolation and biological activity: F. Kuno, et al.; J. Antibiot. 49, 742 (1996) Abstract
Territrems: Naturally Occurring Specific Irreversible Inhibitors of Acetylcholinesterase: J.W. Chen & K.H. Ling; J. Biomed. Sci. 3, 54 (1996) Abstract
Territrem B, a tremorgenic mycotoxin that inhibits acetylcholinesterase with a noncovalent yet irreversible binding mechanism: J.W. Chen, et al.; J. Biol. Chem. 274, 34916 (1999) Abstract; Full Text
Territrems B and C metabolism in human liver microsomes: major role of CYP3A4 and CYP3A5: F.C. Peng, et al.; Toxicology 218, 172 (2006) Abstract
General Information
MANUFACTURER Manufactured by the Kitasato Institute, Tokyo.
Further Categories Containing This Product:
Acetylcholine Esterase / Related Products
 
 
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