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ALX-151-001 Revised 25-Nov-04
β-Amyloid (1-43)
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PRODUCT LINE Neurobiology
PRODUCT CATEGORY beta-Amyloid Peptides
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-151-001-PC01   0.1 mg* 120.00 USD Add To Cart
ALX-151-001-PC05   0.5 mg* 480.00 USD Add To Cart
Product Specification
SEQUENCE: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-Thr-OH
FORMULA: C207H318N56O62S
MW: 4615.3
QUANTITY: *Sold as net peptide weight.
PURITY: ≥96%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Specific Literature References
Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease: D. Goldgaber, et al.; Science 235, 877 (1987) Abstract
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor: J. Kang, et al.; Nature 325, 733 (1987) Abstract
Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state: C.J. Pike, et al.; J. Neurosci. 13, 1676 (1993) Abstract
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Peptides
 
 
ALX-151-002 Revised 07-Mar-05
β-Amyloid (1-42)
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PRODUCT LINE Neurobiology
PRODUCT CATEGORY beta-Amyloid Peptides
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-151-002-PC05   0.5 mg* 350.00 USD Add To Cart
ALX-151-002-P001   1 mg* 620.00 USD Add To Cart
Product Specification
SEQUENCE: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
FORMULA: C203H311N55O60S
MW: 4514.1
QUANTITY: *Sold as net peptide weight.
PURITY: ≥97%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in 5% acetic acid.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Specific Literature References
Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease: D. Goldgaber, et al.; Science 235, 877 (1987) Abstract
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor: J. Kang, et al.; Nature 325, 733 (1987) Abstract
A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease: J. Murrell, et al.; Science 254, 97 (1991) Abstract
Solution structures of beta peptide and its constituent fragments: relation to amyloid deposition: C.J. Barrow & M.G. Zagorski; Science 253, 179 (1991) Abstract
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Peptides
 
 
ALX-151-003 Revised 25-Nov-04
β-Amyloid (1-40)
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PRODUCT LINE Neurobiology
PRODUCT CATEGORY beta-Amyloid Peptides
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-151-003-PC05   0.5 mg* 290.00 USD Add To Cart
ALX-151-003-P001   1 mg* 560.00 USD Add To Cart
Product Specification
SEQUENCE: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH
FORMULA: C194H295N53O58S
MW: 4329.9
QUANTITY: *Sold as net peptide weight.
PURITY: ≥97%
APPEARANCE: White lyophilized powder.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Specific Literature References
Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides: B.A. Yankner, et al.; Science 250, 279 (1990) Abstract
The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease: J.T. Jarrett, et al.; Biochemistry 32, 4693 (1993) Abstract
Structure of amyloid A4-(1-40)-peptide of Alzheimer's disease: H. Sticht, et al.; Eur. J. Biochem. 233, 293 (1995) Abstract
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Peptides
 
 
ALX-151-005 Revised 25-Nov-04
β-Amyloid (1-28)
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PRODUCT LINE Neurobiology
PRODUCT CATEGORY beta-Amyloid Peptides
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-151-005-PC05   0.5 mg* 160.00 USD Add To Cart
ALX-151-005-P001   1 mg* 270.00 USD Add To Cart
Product Specification
SEQUENCE: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH
FORMULA: C145H209N41O46
MW: 3262.5
QUANTITY: *Sold as net peptide weight.
PURITY: ≥97%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Specific Literature References
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor: J. Kang, et al.; Nature 325, 733 (1987) Abstract
Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro: D.A. Kirschner, et al.; PNAS 84, 6953 (1987) Abstract
Brain protein yields clues to Alzheimer's disease: J.L. Marx; Science 243, 1664 (1989) Abstract
Is amyloid deposition in Alzheimer's disease preceded by an environment- induced double conformational transition?: M. Hollosi, et al.; Pept. Res. 2, 109 (1989) Abstract
Amyloid beta protein enhances the survival of hippocampal neurons in vitro: J.S. Whitson, et al.; Science 243, 1488 (1989) Abstract
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Peptides
 
 
ALX-151-007 Revised 14-Dec-04
[Gln11]-β-Amyloid (1-16)
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PRODUCT LINE Neurobiology
PRODUCT CATEGORY beta-Amyloid Peptides
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ALX-151-007-PC05   0.5 mg* 120.00 USD Add To Cart
ALX-151-007-P001   1 mg* 190.00 USD Add To Cart
Product Specification
SEQUENCE: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Gln-Val-His-His-Gln-Lys-OH
FORMULA: C84H119N27O28
MW: 1955.0
CAS NUMBER: 133605-53-5
QUANTITY: *Sold as net peptide weight.
PURITY: ≥97%
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Further Categories Containing This Product:
Peptides
 
 
ALX-151-008 Revised 23-Oct-07
β-Amyloid (25-35)
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PRODUCT LINE Neurobiology
PRODUCT CATEGORY beta-Amyloid Peptides
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-151-008-P001   1 mg* 120.00 USD Add To Cart
ALX-151-008-P005   5 mg* 480.00 USD Add To Cart
Product Specification
SEQUENCE: H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH
FORMULA: C45H81N13O14S
MW: 1060.3
QUANTITY: *Sold as net peptide weight.
PEPTIDE CONTENT: 70-90%
PURITY: ≥99% (HPLC)
APPEARANCE: Lyophilized.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Specific Literature References
Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides: B.A. Yankner, et al.; Science 250, 279 (1990) Abstract
Further Categories Containing This Product:
Peptides
 
 
ALX-151-009 Revised 13-Aug-02
β-Amyloid (10-20)
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PRODUCT LINE Neurobiology
PRODUCT CATEGORY beta-Amyloid Peptides
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ALX-151-009-P001   1 mg* 90.00 USD Add To Cart
ALX-151-009-P005   5 mg* 360.00 USD Add To Cart
Product Specification
SEQUENCE: H-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-OH
FORMULA: C71H99N17O16
MW: 1446.7
QUANTITY: *Sold as net peptide weight.
PURITY: ≥97%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Specific Literature References
A metalloproteinase inhibitor domain in Alzheimer amyloid protein precursor: K. Miyazaki, et al.; Nature 362, 839 (1993) Abstract
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Peptides
 
 
ALX-151-011 Revised 13-Jan-05
β-Amyloid/A4 Protein Precursor [APP] (328-332)
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PRODUCT LINE Neurobiology
PRODUCT CATEGORY beta-Amyloid Peptides
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ALX-151-011-P001   1 mg* 90.00 USD Add To Cart
ALX-151-011-P005   5 mg* 360.00 USD Add To Cart
Product Specification
SEQUENCE: H-Arg-Glu-Arg-Met-Ser-OH
FORMULA: C25H47N11O9S
MW: 677.8
QUANTITY: *Sold as net peptide weight.
PURITY: ≥96%
APPEARANCE: White lyophilized powder.
SOLUBILITY: Soluble in TFA/water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Active domain of the amyloid β/A4 protein precursor (APP) that promotes fibroblast growth.
Product Specific Literature References
Amino acid sequence RERMS represents the active domain of amyloid beta/A4 protein precursor that promotes fibroblast growth: H. Ninomiya, et al.; J. Cell. Biol. 121, 879 (1993) Abstract
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Peptides
 
 
ALX-151-013 Revised 05-Dec-06
Apamin
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY K+ Channel Blockers & Inhibitors
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ALX-151-013-MC05   0.5 mg 150.00 USD Add To Cart
Product Specification
SEQUENCE: H-Cys-Asn-Cys-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys-Ala-Arg-Arg-Cys-Gln-Gln-His-NH2
(Disulfide bonds between Cys1-Cys11and Cys3-Cys15)
FORMULA: C131H131N31O24S4
MW: 2027.3
CAS NUMBER: 24345-16-2
MERCK INDEX: 14: 725
RTECS: CD6899900
SOURCE/HOST: Synthetic.
PURITY: ≥97% (HPLC)
APPEARANCE: Lyophilized.
SOLUBILITY: Soluble in 0.05M acetic acid; slightly soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Originally isolated from Apis mellifera. A small conductance Ca2+-activated K+ channel blocker.
Product Specific Literature References
Toxins in the characterization of potassium channels: N.A. Castle, et al.; TINS 12, 59 (1989), (Review) Abstract
Potassium channel toxins: P.N. Strong; Pharmacol. Ther. 46, 137 (1990) Abstract
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Peptides
 
 
ALX-151-014 Revised 15-Dec-04
cAMP-dependent Protein Kinase Inhibitor (5-24)
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SYNONYMS PKA Inhibitor (5-24)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY PKA Inhibitors
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ALX-151-014-MC05   0.5 mg 90.00 USD Add To Cart
ALX-151-014-M001   1 mg 160.00 USD Add To Cart
Product Specification
SEQUENCE: H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH
FORMULA: C94H148N32O31
MW: 2222.4
PURITY: ≥97%
APPEARANCE: White to off-white powder.
FORMULATION: Lyophilized.
SOLUBILITY: Soluble in water or 5 % acetic acid.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Keep cool and dry.
Product Description
Potent inhibitor of cAMP-dependent protein kinase (PKA). The peptide corresponds to the active site of the skeletal muscle inhibitor protein.
Product Specific Literature References
A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase: H.-C. Cheng, et al.; J. Biol. Chem. 261, 989 (1986) Abstract; Full Text
Phosphorylation of Avena phytochrome in vitro as a probe of light- induced conformational changes: Y.S. Wong, et al.; J. Biol. Chem. 261, 12089 (1986) Abstract; Full Text
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Peptides
 
 
ALX-151-016 Revised 17-Jan-05
cAMP-dependent Protein Kinase Inhibitor (5-22) amide
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SYNONYMS PKA Inhibitor (5-22) amide
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY PKA Inhibitors
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ALX-151-016-MC05   0.5 mg 110.00 USD Add To Cart
ALX-151-016-M001   1 mg 180.00 USD Add To Cart
Product Specification
SEQUENCE: H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2
FORMULA: C84H137N29O26
MW: 1969.2
PURITY: ≥97%
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Potent inhibitor of cAMP-dependent protein kinase (PKA).
Product Specific Literature References
A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase: H.-C. Cheng, et al.; J. Biol. Chem. 261, 989 (1986) Abstract; Full Text
Primary structural determinants essential for potent inhibition of cAMP- dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein: D.B. Glass, et al.; J. Biol. Chem. 264, 8802 (1989) Abstract; Full Text
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Peptides
 
 
ALX-151-017 Revised 15-Dec-04
cAMP-dependent Protein Kinase Inhibitor (14-24) amide
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SYNONYMS PKA Inhibitor (14-24) amide
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY PKA Inhibitors
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-151-017-M001   1 mg 90.00 USD Add To Cart
ALX-151-017-M005