ALEXIS Biochemicals: Farnesylpyrophosphate . triammonium salt

ALX-290-003

Revised 30-Jun-08

Farnesylpyrophosphate . triammonium salt
SYNONYMS	FPP . 3NH₄ 3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol pyrophosphate . 3NH₄
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Farnesylation/Isoprenylation Reagents

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-290-003-C200		200 µg	62.00 USD

Product Specification

FORMULA:	C₁₅H₂₅O₇P₂ . 3NH₄
MW:	379.3 . 54.1
CAS NUMBER:	13058-04-3
PURITY:	≥98% (TLC)
APPEARANCE:	Liquid. Solution in 0.25M ammonium bicarbonate containing 70% ethanol.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Store solutions at -20°C for up to 3 months.
HANDLING:	Protect from light and moisture.

Product Description

Farnesyl donor in enzymatic protein farnesylation catalyzed by farnesyltransferase.

Product Specific Literature References

Tautomycin from the bacterium Streptomyces verticillatus. Another potent and specific inhibitor of protein phosphatases 1 and 2A: C. MacKintosh & S. Klumpp; FEBS Lett. 277, 137 (1990) Abstract
M. Ubukata, et al.; J. C. S. Chem. Commun. 244 (1990)
Divalent cation and prenyl pyrophosphate specificities of the protein farnesyltransferase from rat brain, a zinc metalloenzyme: Y. Reiss, et al.; J. Biol. Chem. 267, 6403 (1992) Abstract; Full Text
Inhibitors of Ras farnesyltransferases: F. Tamanoi; TIBS 18, 349 (1993), (Review) Abstract
Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic: J.B. Gibbs, et al.; Cell 77, 175 (1994) Abstract

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