ALEXIS Biochemicals: Fascaplysin

ALX-270-300

Revised 05-Apr-08

Fascaplysin
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Natural Products for Cell Cycle Research

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-300-M001		1 mg	60.00 USD
ALX-270-300-M005		5 mg	240.00 USD

Product Specification

FORMULA:	C₁₈H₁₁N₂OCl
MW:	306.8
SOURCE/HOST:	Synthetic.
PURITY:	≥98%
APPEARANCE:	Brown powder.
SOLUBILITY:	Soluble in DMSO or methanol.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
HANDLING:	Keep under inert gas. Protect from light.
HAZARD:	TOXIC.

Product Description

Originally isolated from a marine sponge. Selective CDK4/cyclin D1 (IC₅₀=350nM) inhibitor (in an ATP competitive manner).

Product Specific Literature References

Fascaplysin, an unusual antimicrobial pigment from the marine sponge Fascaplysinopsis sponge: D.M. Roll, et al.; J. Org. Chem. 53, 3276 (1988)
A new bioactive sesterterpene and antiplasmodial alkaloids from the marine sponge hyrtios cf. erecta: G. Kirsch, et al.; J. Nat. Prod. 63, 825 (2000) Abstract
Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product: R. Soni, et al.; BBRC 275, 877 (2000) Abstract
DNA binding properties of the marine sponge pigment fascaplysin: A. Hormann, et al.; Bioorg. Med. Chem. 9, 917 (2001) Abstract

Further Categories Containing This Product:

CDK & Cyclin Inhibitors • Alkaloids

another CS2 website

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.