ALEXIS Biochemicals: Fc (human):TNF-α (human), Soluble (recombinant)

ALX-522-087

Revised 07-Feb-06

Fc (human):TNF-α (human), Soluble (recombinant)
SYNONYMS	Fc (human):Tumor Necrosis Factor-α (human), Soluble (recombinant) Fc (human):TNFSF2 (human), Soluble (recombinant)
PRODUCT LINE	Chemokines & Cytokines
PRODUCT CATEGORY	TNF-alpha

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-522-087-C010		10 µg	395.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse
MW:	~48kDa
SOURCE/HOST:	Produced in CHO cells. The extracellular domain of human TNF-α (aa 85-233) is fused at the N-terminus to the Fc portion of human IgG1 and a linker peptide (20 aa).
CONCENTRATION:	0.1mg/ml after reconstitution.
PURITY:	≥95% (SDS-PAGE)
FORMULATION:	Lyophilized. Contains PBS.
ENDOTOXIN CONTENT:	<0.1EU/µg protein (LAL test; BioWhittaker).
RECONSTITUTION:	Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
SPECIFICITY:	Binds to human and mouse TNF-R1 and TNF-R2.
BIOLOGICAL ACTIVITY:	Induces killing of WEHI-164 cells in a concentration range of 0.5-2ng/ml (does not require an enhancer).
APPLICATION:	Flow Cytometry (1:100) Immunoprecipitation (1:500)
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 6 months after receipt when stored at -20°C.
HANDLING:	After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

General Information

MANUFACTURER

Manufactured by Apotech Corporation.

General Literature References

Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction: J.R. Muppidi, et al.; Immunity 21, 461 (2004) Abstract

Further Categories Containing This Product:

Recombinant Proteins/Fusion Proteins

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