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ALX-380-227 Revised 05-Apr-08
Geninthiocin
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SYNONYMS 14-Demethylberinamycin
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Antibiotics Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-380-227-MC05   0.5 mg 360.00 USD Add To Cart
Product Specification
FORMULA: C50H49N15O15S
MW: 1132.1
CAS NUMBER: 158792-27-9
SOURCE/HOST: Isolated from Streptomyces sp. MST-AS5991.
PURITY: ≥95% (HPLC)
APPEARANCE: White to off-white amorphous powder.
SOLUBILITY: Soluble in methanol, dimethyl formamide or DMSO.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C

Product Description
Antibiotic. Potent activator of the tipA gene, a bacterial transcription regulator involved in multidrug resistance.
Product Specific Literature References
Microbial metabolites with tipA promoter inducing activity. II. Geninthiocin, a novel thiopeptide produced by Streptomyces sp. DD84: B.S. Yun, et al.; J. Antibiot. (Tokyo) 47, 969 (1994) Abstract
Structural basis for antibiotic recognition by the TipA class of multidrug-resistance transcriptional regulators: J.D. Kahmann, et al.; EMBO J. 22, 1824 (2003) Abstract; Full Text
 
 
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