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ALX-420-016 Revised 30-Nov-06
Glyco-SNAP-1
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SYNONYMS N-(β-D-Glucopyranosyl)-N2-acetyl-S-nitroso-D,L-penicillaminamide
PRODUCT LINE Nitric Oxide Pathway
PRODUCT CATEGORY Nitric Oxide Donors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-420-016-M005   5 mg 140.00 USD Add To Cart
Product Specification
FORMULA: C13H23N3O8S
MW: 381.4
PURITY: ≥96%
APPEARANCE: Green crystalline solid.
SOLUBILITY: Soluble in water or methanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C

Product Description
Highly water soluble nitric oxide (NO) donor, which is relatively stable at high pH (pH 8-9). See also SNAP (Prod. No. ALX-420-003).
Product Specific Literature References
Glyco-S-Nitrosothiols, A Novel Class of NO Donor Compounds: J. Ramirez, et al.; Bioorg. Med. Chem. Lett. 6, 2575 (1996)
IFN-gamma inhibits AP-1 binding activity in human brain-derived cells through a nitric oxide dependent mechanism: K. Conant, et al.; J. Neuroimmunol. 88, 39 (1998) Abstract
In vitro cytotoxicity of glyco-S-nitrosothiols. a novel class of nitric oxide donors: H. Babich & H.L. Zuckerbraun; Toxicol. In Vitro 15, 181 (2001) Abstract
Vascular endothelial growth factor receptor-2-mediated mitogenesis is negatively regulated by vascular endothelial growth factor receptor-1 in tumor epithelial cells: C. Dunk & A. Ahmed; Am. J. Pathol. 158, 265 (2001) Abstract; Full Text
Structural and kinetic modifications of aldose reductase by S-nitrosothiols: S. Srivastava, et al.; Biochem. J. 358, 111 (2001) Abstract; Full Text
A predominant role for cAMP-dependent protein kinase in the cGMP-induced phosphorylation of vasodilator-stimulated phosphoprotein and platelet inhibition in humans: Z. Li, et al.; Blood 101, 4423 (2003) Abstract; Full Text
GPIb-dependent platelet activation is dependent on Src kinases but not MAP kinase or cGMP-dependent kinase: S.J. Marshall, et al.; Blood 103, 2601 (2004) Abstract; Full Text
 
 
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