ALEXIS Biochemicals: Guanosine 3',5'-cyclic Monophosphate . sodium salt

ALX-480-059

Revised 09-Mar-06

Guanosine 3',5'-cyclic Monophosphate . sodium salt
SYNONYMS	cGMP . Na
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	cGMP Derivatives

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-480-059-M025		25 mg	25.00 USD
ALX-480-059-M100		100 mg	95.00 USD

Product Specification

FORMULA:	C₁₀H₁₁N₅O₇P . Na
MW:	344.2 . 23.0
CAS NUMBER:	40732-48-7
MERCK INDEX:	14: 2709
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Intracellular messenger implicated in mediating action of nitric oxide (NO) in many cell types. Target receptors for the second messenger guanosine 3',5'-cyclic monophosphate (cGMP) include protein kinase G (PKG) isozymes, cGMP-dependent ion channels as well as cGMP-responsive phosphodiesterases. In presence of corresponding phosphodiesterases cGMP is metabolized rapidly. Suppresses apoptosis.

Product Specific Literature References

Cyclic GMP metabolism and involvement in biological regulation: N.D. Goldberg & M.K. Haddox; Ann. Rev. Biochem. 46, 823 (1977) Abstract
Interleukin-1 beta suppresses apoptosis in rat ovarian follicles by increasing nitric oxide production: S.Y. Chun, et al.; Endocrinology 136, 3120 (1995) Abstract

Further Categories Containing This Product:

Guanylyl Cyclases, Guanosine Phosphate Metabolism / Related Products • Apoptosis Inducers & Inhibitors Other Products

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