ALEXIS Biochemicals: HSD Inhibitor 23

ALX-270-474

Revised 22-Oct-07

HSD Inhibitor 23
SYNONYMS	N-(5-Hydroxytricyclo[3.3.1.13,7]dec-2-yl)-α,α-dimethyl-4-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazineacetamide
PRODUCT LINE	DNA Regulation / Transcription
PRODUCT CATEGORY	Glucocorticoids & Glucocorticoid Receptors/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-474-M001		1 mg	190.00 USD

Product Specification

FORMULA:	C₂₄H₃₃F₃N₄O₂
MW:	466.5
CAS NUMBER:	868604-75-5
PURITY:	≥95%
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.
IDENTITY:	Determined by ¹H-NMR, ¹³C-NMR and MS.

Product Description

Selective, potent and cell permeable small molecule inhibitor of 11-β-hydroxysteroid dehydrogenase.

Product Specific Literature References

Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: J.J. Rohde, et al.; J. Med. Chem. 50, 149 (2007) Abstract; Full Text

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