ALEXIS Biochemicals: HT-2 Toxin

ALX-630-113

Revised 13-Jun-08

HT-2 Toxin
SYNONYMS	15-Acetoxy-3α,4β-dihydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Mycotoxins

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-630-113-M001		1 mg	110.00 USD
ALX-630-113-M005		5 mg	440.00 USD

Product Specification

FORMULA:	C₂₂H₃₂O₈
MW:	424.5
CAS NUMBER:	26934-87-2
RTECS:	YD0050000
SOURCE/HOST:	Semisynthetic, derived from T2 toxin from Fusarium tricinctum.
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white crystalline solid.
SOLUBILITY:	Soluble in 100% ethanol, DMSO or ethyl acetate; poorly soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HAZARD:	VERY TOXIC.

Product Description

Trichothecene group mycotoxin. Induces apoptosis

Product Specific Literature References

Structure-function relationship of T-2 toxin and its metabolites in inducing thymic apoptosis in vivo in mice: Z. Islam, et al.; Biosci. Biotechnol. Biochem. 62, 1492 (1998) Abstract; Full Text
Mechanisms involved in the induction of apoptosis by T-2 and HT-2 toxins in HL-60 human promyelocytic leukemia cells: J.A. Holme, et al.; Cell Biol. Toxicol. 19, 53 (2003) Abstract
A practical method for measuring deoxynivalenol, nivalenol, and T-2 + HT-2 toxin in foods by an enzyme-linked immunosorbent assay using monoclonal antibodies: T. Yoshizawa, et al.; Biosci. Biotechnol. Biochem. 68, 2076 (2004) Abstract; Full Text