ALEXIS Biochemicals: IL-1β (human) (recombinant) (cell culture grade)

ALX-520-001

Revised 11-Apr-08

IL-1β (human) (recombinant) (cell culture grade)
SYNONYMS	Interleukin-1β (human) (recombinant) (cell culture grade) IL-1F2 (human) (recombinant) (cell culture grade)
PRODUCT LINE	Chemokines & Cytokines
PRODUCT CATEGORY	Interleukins

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-520-001-C010		10 µg	297.00 USD

Product Specification

MW:	~17kDa.
CAS NUMBER:	97599-21-8
MERCK INDEX:	14: 4993
SOURCE/HOST:	Produced in E. coli.
PURITY:	≥98% (SDS-PAGE)
FORMULATION:	Lyophilized. Salt-free.
ENDOTOXIN CONTENT:	<1EU/µg protein.
RECONSTITUTION:	Reconstitute with water, PBS or aqueous buffer to a concentration of 100µg/ml. For further dilution carrier protein (~1%) should be added to avoid loss of bioactivity.
BIOLOGICAL ACTIVITY:	Exerts in vitro biological activity in the range of 0.1-10ng/ml.
SPECIFIC ACTIVITY:	≥1x10⁷U/mg protein. Determined by proliferation assay using human TF-1 (T. Kitamura, et al.; Int. Immunol. 3, 571 (1991)). The ED₅₀ for this effect is typically 0.2-2ng/ml. Results were compared with the international IL-1 reference standard preparation (WHO 86/680, NIBSC).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Product Description

Potent immuno-modulator. Mediates a wide range of immune and inflammatory responses including the activation of B and T cells.

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