ALEXIS Biochemicals: IL-1 Receptor Type I (human):Fc (human) (recombinant)

ALX-522-057

Revised 01-Oct-08

IL-1 Receptor Type I (human):Fc (human) (recombinant)
SYNONYMS	IL-1RI (human):Fc (human) (recombinant) Interleukin-1 Receptor Type I (human):Fc (human) (recombinant) CD121a (human):Fc (human) (recombinant)
PRODUCT LINE	Chemokines & Cytokines
PRODUCT CATEGORY	Interleukin Receptors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-522-057-C050		50 µg	365.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human
MW:	~83kDa (SDS-PAGE).
SOURCE/HOST:	Produced in HEK 293 cells. Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused to the Fc portion of human IgG1.
CONCENTRATION:	1mg/ml after reconstitution.
PURITY:	≥90% (SDS-PAGE)
FORMULATION:	Lyophilized. Contains PBS.
ENDOTOXIN CONTENT:	<0.1EU/µg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION:	Reconstitute with 50µl sterile water.
SPECIFICITY:	Binds to human IL-1 (interleukin-1).
BIOLOGICAL ACTIVITY:	Blocks IL-1 activity.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 6 months after receipt when stored at -20°C.
HANDLING:	Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.

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General Information

MANUFACTURER

Manufactured by Apotech Corporation.

General Literature References

Cytokine receptors and signal transduction: A. Miyajima, et al.; Annu. Rev. Immunol. 10, 295 (1992) Abstract
cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily: J.E. Sims, et al.; Science 241, 585 (1988) Abstract
The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense: L.A. O'Neill; Sci. STKE 2000, RE1 (2000) Abstract
IL-1 and IL-18 receptors, and their extended family: J.E. Sims, et al.; Curr. Opin. Immunol. 14, 117 (2002) Abstract