ALEXIS Biochemicals: INDO 1 . pentapotassium salt

ALX-450-004

Revised 04-Feb-05

INDO 1 . pentapotassium salt
SYNONYMS	1-[2-Amino-5-(6-carboxyindol-2-yl)phenoxy]-2-(2'-amino-5'-methylphenoxy)ethane-N,N,N',N'-tetraacetic acid . 5K
PRODUCT LINE	Other Products
PRODUCT CATEGORY	Dyes/Stains/Fluorescent Probes/Fluorescent Labels

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-450-004-M001		1 mg	95.00 USD

Product Specification

FORMULA:	C₃₂H₂₆N₃O₁₂ . 5K
MW:	644.6 . 195.5
CAS NUMBER:	132319-56-3
PURITY:	≥97%
APPEARANCE:	Off-white solid.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.

Product Description

Ca²⁺ chelator and indicator of intracellular and extracellular Ca²⁺. Particularly useful in flow cytometry studies.

Product Specific Literature References

New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures: R.Y. Tsien; Biochemistry 19, 2396 (1980) Abstract
A new generation of Ca2+ indicators with greatly improved fluorescence properties: G. Grynkiewicz, et al.; J. Biol. Chem. 260, 3340 (1985) Abstract; Full Text
Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3. Simultaneous use of indo-1 and immunofluorescence with flow cytometry: P.S. Rabinovitch, et al.; J. Immunol. 137, 952 (1986) Abstract
CD5 antibodies increase intracellular ionized calcium concentration in T cells: C.H. June, et al.; J. Immunol. 138, 2782 (1987) Abstract
Diminished calcium influx in lectin-stimulated T cells from old mice: R.A. Miller, et al.; J. Cell. Physiol. 132, 337 (1987) Abstract
Calcium mobilization in human platelets using indo-1 and flow cytometry: L.K. Jennings, et al.; Blood 74, 2674 (1989) Abstract
Analysis of cytosolic ionized calcium variation in polymorphonuclear leukocytes using flow cytometry and Indo-1 AM: M. Lopez, et al.; Cytometry 10, 165 (1989) Abstract
Cytosolic and vacuolar Ca2+ concentrations in yeast cells measured with the Ca2+-sensitive fluorescence dye indo-1: D. Halachmi & Y. Eilam; FEBS Lett. 256, 55 (1989) Abstract
Intracellular Ca2+ measurement with Indo-1 in substrate-attached cells: advantages and special considerations: M. Wahl, et al.; Cell Calcium 11, 487 (1990) Abstract
Calcium changes in immune complex-stimulated human neutrophils. Simultaneous measurement of receptor occupancy and activation reveals full population stimulus binding but subpopulation activation: B.A. Brunkhorst, et al.; J. Biol. Chem. 266, 13035 (1991) Abstract; Full Text

Further Categories Containing This Product:

Calcium Indicators/Probes • MDR Other Products • Calcium Chelators/Caged Calcium Chelators

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