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ALX-210-574
Revised 18-Oct-07
Polyclonal Antibody to NF-κB (p65)
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
NF-kB Transcription Factors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-574-R100
100 µl
280.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST:
From rabbit.
FORMULATION:
Liquid. Neat serum containing 0.05% sodium azide.
IMMUNOGEN:
Recombinant human NF-κB (p65 subunit).
SPECIFICITY:
Recognizes human and mouse NF-κB (p65 subunit).
APPLICATION:
Immunocytochemistry (1:500-1:1’000)
Immunohistochemistry (paraffin sections (1:500-1:1’000))
Immunoprecipitation (2µg)
Western Blot (1:2’000-1:5’000)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-80°C
USE/STABILITY:
Stable for one week when stored at +4°C.
HANDLING:
After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles.
Product Specific Literature References
Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1:
P.O. Hassa, et al.; J. Biol. Chem.
278
, 45145 (2003)
Abstract
;
Full Text
Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcription:
P.O. Hassa, et al.; J. Biol. Chem.
280
, 40450 (2005)
Abstract
;
Full Text
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-576
Revised 18-Oct-07
Polyclonal Antibody to NF-κB (p50)
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
NF-kB Transcription Factors/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-576-R100
100 µl
280.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
FORMULATION:
Liquid. Neat serum containing 0.05% sodium azide.
IMMUNOGEN:
Recombinant human NF-κB (p50 subunit).
SPECIFICITY:
Recognizes human NF-κB (p50 subunit).
APPLICATION:
Western Blot (1:1’000)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-80°C
USE/STABILITY:
Stable for one week when stored at +4°C.
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C.
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-637
Revised 12-Oct-07
Polyclonal Antibody to Toll-like Receptor 9 (mouse)
SYNONYMS
anti-TLR9 (mouse) PAb
anti-CD289 (mouse) PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
TLR Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-637-C200
200 µg
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST:
From goat.
CONCENTRATION:
2mg/ml.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 204-224 (L
204
SLKYNNLTKVPRQLPPSLEY
224
C) of the N-terminal domain of mouse TLR9 (Toll-like receptor 9).
SPECIFICITY:
Recognizes mouse TLR9. Cross-reacts with human TLR9.
APPLICATION:
Immunocytochemistry (acetone fixed cells (>1:400))
Immunohistochemistry (paraffin sections (>1:250))
Western Blot (>1:1’000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
After opening, prepare aliquots and store at -20°C. For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-168-013
.
Product Images
Please click on thumbnails to enlarge.
Further Categories Containing This Product:
CD Antibodies
•
Polyclonal Antibodies
ALX-210-638
Revised 25-Sep-07
Polyclonal Antibody to Toll-like Receptor 4
SYNONYMS
anti-TLR4 PAb
anti-CD284 PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
TLR Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-638-C200
200 µg
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST:
From goat.
CONCENTRATION:
2mg/ml.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 161-192 (L
161
IQSFKLPEYFSNLTNLEHLDLSSNKIQSIYC
192
) of the N-terminal domain of human TLR4 (Toll-like receptor 4).
SPECIFICITY:
Recognizes human and mouse TLR4.
APPLICATION:
Immunocytochemistry (acetone fixed cells (>1:400))
Immunohistochemistry (paraffin sections (>1:250))
Western Blot (>1:1’000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap. After opening, prepare aliquots and store at -20°C.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-168-014
.
Product Images
Please click on thumbnails to enlarge.
Related Products
ALX-168-014
Blocking Peptide for PAb to Toll-like Receptor 4 (Prod. No.
ALX-210-638
)
Further Categories Containing This Product:
CD Antibodies
•
Polyclonal Antibodies
ALX-210-639
Revised 16-Oct-07
Polyclonal Antibody to Toll-like Receptor 8
SYNONYMS
anti-TLR8 PAb
anti-CD288 PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
TLR Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-639-C200
200 µg
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST:
From goat.
CONCENTRATION:
2mg/ml.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 81-109 (CE
81
SFQGLQNLTKINLNHNPNVQHQNGNPGI
109
) of the N-terminal domain of human TLR8 (Toll-like receptor 8).
SPECIFICITY:
Recognizes human and mouse TLR8.
APPLICATION:
Immunocytochemistry (acetone fixed cells (>1:400))
Immunohistochemistry (paraffin sections (>1:250))
Western Blot (>1:1’000)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap. After opening, prepare aliquots and store at -20°C.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-168-015
.
Product Images
Please click on thumbnails to enlarge.
Related Products
ALX-168-015
Blocking Peptide for PAb to Toll-like Receptor 8 (Prod. No.
ALX-210-639
)
Further Categories Containing This Product:
CD Antibodies
•
Polyclonal Antibodies
ALX-210-642
Revised 12-Oct-07
Polyclonal Antibody to Toll-like Receptor 9 (human)
SYNONYMS
anti-TLR9 (human) PAb
anti-CD289 (human) PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
TLR Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-642-C200
200 µg
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST:
From goat.
CONCENTRATION:
1mg/ml.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 205-233 (CS
205
LKYNNLTVVPRNLPSSLEYLLLSYNRIVKL
235
) of the N-terminal domain of human TLR9 (Toll-like receptor 9).
SPECIFICITY:
Recognizes human TLR9. Cross-reacts with mouse TLR9.
APPLICATION:
Immunocytochemistry (acetone fixed cells (>1:400))
Immunohistochemistry (paraffin sections (>1:250))
Western Blot (>1:1’000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-168-016
.
Product Images
Please click on thumbnails to enlarge.
Related Products
ALX-168-016
Blocking Peptide for PAb to to Toll-like Receptor 9 (human) (Prod. No.
ALX-210-642
)
Further Categories Containing This Product:
CD Antibodies
•
Polyclonal Antibodies
ALX-210-643
Revised 23-Oct-07
Polyclonal Antibody to Toll-like Receptor 10 (human)
SYNONYMS
anti-TLR10 (human) PAb
anti-CD290 (human) PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
TLR Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-643-C200
200 µg
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From goat.
CONCENTRATION:
1mg/ml.
PURITY DETAIL:
Epitope affinity-purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 81-111 (CH
81
NRIQQLDLKTFEFNKELRYLDLSNNRLKSV
111
) of human TLR10 (Toll-like receptor 10).
SPECIFICITY:
Recognizes human TLR10.
APPLICATION:
Immunocytochemistry (acetone fixed cells (1:400))
Immunohistochemistry (paraffin sections (>1:250))
Western Blot (1:1'000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-168-017
.
Product Images
Please click on thumbnails to enlarge.
Related Products
ALX-168-017
Blocking Peptide for PAb to Toll-like Receptor 10 (Prod. No.
ALX-210-643
)
ALX-804-407
Monoclonal Antibody to Toll-like Receptor 10 (human) (158C1114)
Further Categories Containing This Product:
CD Antibodies
•
Polyclonal Antibodies
ALX-210-709
Revised 03-Mar-05
Polyclonal Antibody to COX
SYNONYMS
anti-Cyclooxygenase PAb
anti-Prostaglandin H Synthase PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
COX Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-709-1
1 Vial
233.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
Rat
Sheep
SOURCE/HOST:
From rabbit.
QUANTITY:
Sufficient for 10 immunoblots.
FORMULATION:
Lyophilized IgG fraction from rabbit antiserum.
IMMUNOGEN:
Purified sheep seminal vesicle COX-1 (cyclooxygenase 1) [1].
SPECIFICITY:
Recognizes mouse, rat and sheep COX-1 and COX-2.
APPLICATION:
Western Blot (1:1'000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
Product Specific Literature References
[1]
Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence
:
D.L. DeWitt & W.L. Smith; PNAS
85
, 1412 (1988)
Abstract
[2]
Immunocytochemical localization of cyclooxygenase in the rat lens
:
D.R. Zheng, et al.; Invest. Ophthalmol. Vis. Sci.
33
, 178 (1992)
Abstract
[3]
Eicosanoid metabolism in cholesterol-enriched arterial smooth muscle cells. Evidence for reduced posttranscriptional processing of cyclooxygenase I and reduced cyclooxygenase II gene expression
:
K.B. Pomerantz, et al.; Biochemistry
32
, 13624 (1993)
Abstract
[4]
Molecular cloning, functional expression, and selective regulation of ovine prostaglandin H synthase-2
:
V. Zhang, et al.; BBRC
227
, 499 (1996)
Abstract
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-710
Revised 10-Jul-08
Polyclonal Antibody to COX-1
SYNONYMS
anti-Cyclooxygenase 1 PAb
anti-Prostaglandin H Synthase 1 PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
COX Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-710-1
1 Vial
313.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Sheep
Pig
Others
SOURCE/HOST:
From rabbit.
QUANTITY:
200μg lyophilized antiserum
FORMULATION:
Lyophilized.
RECONSTITUTION:
Reconstitute with 200µl distilled water.
IMMUNOGEN:
Synthetic peptide corresponding to aa 272-282 (L
272
MHYPRGIPPQ
282
) [1,2] of sheep seminal vesicle COX-1 (cyclooxygenase 1).
SPECIFICITY:
Recognizes human, sheep and bovine endothelial COX-1. Also recognizes pig COX-1. Does not cross-react with mouse or rat COX-1 or human, mouse or sheep COX-2.
APPLICATION:
Immunocytochemistry
Immunohistochemistry
Western Blot (1:500)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
After reconstitution, prepare aliquots and store at -20°C.
Product Specific Literature References
[1]
Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence
:
D.L. DeWitt & W.L. Smith; PNAS
85
, 1412 (1988)
Abstract
[2]
The orientation of prostaglandin endoperoxide synthases-1 and -2 in the endoplasmic reticulum
:
J.C. Otto & W.L. Smith; J. Biol. Chem.
269
, 19868 (1994)
Abstract
;
Full Text
[3]
Expression of prostaglandin endoperoxide H synthase 1 and 2 in human placenta at term
:
L. Macchia, et al.; BBRC
233
, 496 (1997)
Abstract
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-711
Revised 06-Jan-06
Polyclonal Antibody to COX-2
SYNONYMS
anti-Cyclooxygenase 2 PAb
anti-Prostaglandin H Synthase 2 PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
COX Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-711-1
1 Vial
189.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Sheep
Monkey
Others
SOURCE/HOST:
From rabbit.
FORMULATION:
Lyophilized from ~50µl purified antiserum.
RECONSTITUTION:
Reconstitute with 100µl distilled water containing 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 584-598 (S
584
HSRLDDINPTVLIK
598
) of mouse COX-2 (cyclooxygenase 2).
SPECIFICITY:
Recognizes human, mouse, rat, monkey, sheep and guinea pig COX-2. Does not cross-react with COX-1.
APPLICATION:
Immunohistochemistry
(frozen sections, paraffin sections;
suggested starting dilution 1:300 -1:600)
Western Blot
(1:1'000).
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 3 years after receipt when stored at -20°C. After reconstitution store at +4°C.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-153-063
.
Related Products
ALX-153-063
Blocking Peptide for PAb to COX-2 (mouse) (Prod. No.
ALX-210-711
and
ALX-210-726
)
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-712
Revised 17-Apr-08
Polyclonal Antibody to COX-2
SYNONYMS
anti-Cyclooxygenase 2 PAb
anti-Prostaglandin H Synthase 2 PAb
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
COX Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-712-1
1 Vial
269.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Sheep
Others
SOURCE/HOST:
From rabbit.
CONCENTRATION:
FORMULATION:
Liquid
