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Statins / Related Products
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ALX-270-466 Revised 14-Sep-07
Fluvastatin . sodium salt
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PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Statins / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-270-466-M010   10 mg 48.00 USD Add To Cart
ALX-270-466-M050   50 mg 190.00 USD Add To Cart
Product Specification
FORMULA: C24H25FNO4 . Na
MW: 410.5 . 23.0
CAS NUMBER: 93957-54-1
MERCK INDEX: 14: 4218
RTECS: MJ9675050
SOURCE/HOST: Synthetic.
PURITY: ≥98%
APPEARANCE: Off-white to light yellow solid.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
USE/STABILITY: Stock solutions are stable for up to 6 months when stored at -20°C.
HANDLING: Protect from light.
HAZARD: TOXIC. MAY BE TERATOGENIC.

Product Description
Anticholesterol agent. HMG-CoA reductase inhibitor and antioxidant.
Product Specific Literature References
Folate and carcinogenesis: an integrated scheme: S.W. Choi and J.B. Mason; J. Nutr. 130, 129 (2000) Abstract; Full Text
Effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on nitric oxide-induced hydroxyl radical generation in the rat heart: T. Obata, et al.; Biochim. Biophys. Acta 1536, 55 (2001) Abstract
Antioxidative effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on peroxidation of phospholipid liposomes: A. Yamamoto, et al.; J. Pharm. Pharmacol. 53, 227 (2001) Abstract
Further Categories Containing This Product:
Obesity & Diabetes Other Products
 
 
ALX-430-103 Revised 14-Mar-05
Lovastatin
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SYNONYMS Mevinolin
6-α-Methylcompactin
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Statins / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-430-103-M050   50 mg 60.00 USD Add To Cart
Product Specification
FORMULA: C24H36O5
MW: 404.5
CAS NUMBER: 75330-75-5
MERCK INDEX: 14: 5586
PURITY: ≥98%
SOLUBILITY: Soluble in DMSO, chloroform or acetone; sparingly soluble in acetonitrile, methanol or 100 % ethanol; insoluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: +20°C
Product Description
Inhibitor of HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis. Induces apoptosis in cancer cells.
Product Specific Literature References
Statins as a newly recognized type of immunomodulator: B. Kwak, et al.; Nat. Med. 6, 1399 (2000) Abstract
Further Categories Containing This Product:
Apoptosis Inducers & Inhibitors Other Products • Ubiquitination Other Products
 
 
ALX-430-104 Revised 18-Apr-07
Simvastatin
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SYNONYMS Zocor
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Statins / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-430-104-M050   50 mg 85.00 USD Add To Cart
Product Specification
FORMULA: C25H38O5
MW: 418.6
CAS NUMBER: 79902-63-9
MERCK INDEX: 14: 8539
RTECS: EK7798000
PURITY: ≥98%
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in DMSO, 100% ethanol or methanol. Insoluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: +20°C
USE/STABILITY: Store solutions at -20°C.

Product Description
HMG-CoA reductase inhibitor. Synthetic analog of lovastatin (Prod. No. ALX-430-103). Antihyperlipidemic.
Product Specific Literature References
Lovastatin and simvastatin are modulators of the proteasome: C. Wojcik, et al.; Int. J. Biochem. Cell Biol. 32, 957 (2000) Abstract
Further Categories Containing This Product:
Antitumor Agents (Anti-proliferative) • Antitumor Agents (Enzyme Inhibitors) • Ubiquitination Other Products
 
 
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