ALEXIS Biochemicals: Isofistularin-3

ALX-350-157

Revised 18-Feb-08

Isofistularin-3
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Alkaloids

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-157-M001		1 mg	160.00 USD

Product Specification

FORMULA:	C₃₁H₃₀Br₆N₄O₁₁
MW:	1114.0
CAS NUMBER:	87099-50-1
SOURCE/HOST:	Isolated from Aplysina aerophoba.
PURITY:	≥97% (HPLC)
APPEARANCE:	White to off-white amorphous solid.
SOLUBILITY:	Soluble in DMSO or 100% ethanol.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.
IDENTITY:	Identity determined by ¹H-NMR.

Product Description

Cytotoxic alkaloid. Shows antibiotic properties. Inhibits cell growth in vitro.

Product Specific Literature References

The bromo-compounds of the true sponge Verongia aerophoba: G. Cimino, et al.; Tetrahedron Lett. 24, 3029 (1983)
Antibiotic and cytotoxic activity of brominated compounds from the marine sponge Verongia aerophoba: R. Teeyapant, et al.; Z. Naturforsch. 48, 939 (1993) Abstract
Two unprecedented dibromotyrosine-derived alkaloids from the Brazilian endemic marine sponge Aplysina caissara: B.M. Saeki, et al.; J. Nat. Prod. 65, 796 (2002) Abstract
Chemical defense of Mediterranean sponges Aplysina cavernicola and Aplysina aerophoba: C. Thoms, et al.; Z. Naturforsch. 59, 113 (2004) Abstract
Stereochemical heterogeneity in Verongid sponge metabolites. Absolute stereochemistry of (+)-fistularin-3 and (+)-11-epi-fistularin-3 by microscale LCMS-Marfey’s analysis: E.W. Rogers, et al.; J. Nat. Prod. 68, 891 (2005) Abstract
Antimycobacterial brominated metabolites from two species of marine sponges: M.F. de Oliveira, et al.; Planta Med. 72, 437 (2006) Abstract

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Natural Products with Antibiotic Activity

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