ALEXIS Biochemicals: Kanamycin A . sulfate

ALX-380-275

Revised 07-Apr-08

Kanamycin A . sulfate
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antibiotics Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-275-G001		1 g	20.00 USD
ALX-380-275-G005		5 g	80.00 USD

Product Specification

FORMULA:	C₁₈H₃₆N₄O₁₁ . H₂SO₄
MW:	484.5 . 98.1
CAS NUMBER:	25389-94-0
MERCK INDEX:	14: 5281
RTECS:	NZ3225030
SOURCE/HOST:	Isolated from Streptomyces kanamyceticus.
APPEARANCE:	White to off-white crystalline powder.
SOLUBILITY:	Soluble in water (50mg/ml).
ACTIVITY:	Potency is >750µg/ml (on dry basis).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Aminoglycoside antibiotic. Binds to the 70S ribosomal subunit. Inhibits translocation and elicits miscoding. Interaction with ribosomes may be prevented by aminoglycoside modifying enzymes. Effective against Gram-negative and Gram-positive bacteria and mycoplasma.

Product Specific Literature References

Studies on Streptomyces kanamyceticus, producer of kanamycin: Y. Okami, et al.; J. Antibiot. 12, 252 (1959) Abstract
Infection of the protoplasts of Streptomyces kanamyceticus with deoxyribonucleic acid preparation from actinophage PK-66: M. Okanishi, et al.; J. Bacteriol. 92, 1850 (1966) Abstract; Full Text
The total synthesis of kanamycin A: S. Umezawa, et al.; J. Antibiot. 21, 367 (1968) Abstract
Utilization of carbon and nitrogen sources by Streptomyces kanamyceticus for kanamycin production: K. Basak & S.K. Majumdar; Antimicrob. Agents Chemother. 4, 6 (1973) Abstract; Full Text
Interaction of kanamycin A and kanamycin B with phospholipids: M.W. Yung & C. Green; J. Antibiot. 40, 862 (1987) Abstract
Antibiotic MICs and short time-killing against Helicobacter pylori: therapeutic potential of kanamycin: Y. Irie, et al.; J. Antimicrob. Chemother. 40, 235 (1997) Abstract

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