ALEXIS Biochemicals: Ketanserin . tartrate

ALX-550-051

Revised 27-Aug-07

Ketanserin . tartrate
SYNONYMS	3-[2-[4-(4-Fluorobenzoyl)-1-piperdinyl)ethyl]-2,4(1H,3H)-quinazolinedione tartrate
PRODUCT LINE	Neurobiology
PRODUCT CATEGORY	Serotonergics & Serotonin Receptors / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-550-051-M010		10 mg	35.00 USD
ALX-550-051-M050		50 mg	110.00 USD

Product Specification

FORMULA:	C₂₂H₂₂FN₃O₃ . C₄H₆O₆
MW:	395.4 . 150.1
CAS NUMBER:	83846-83-7
MERCK INDEX:	14: 5296
RTECS:	VA1411195
PURITY:	≥98%
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in DMSO; slightly soluble in water (4mg/ml) or 100% ethanol (3mg/ml).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C
HANDLING:	Protect from moisture.
HAZARD:	TOXIC.

Product Description

Selective 5-HT_2A serotonin receptor antagonist.

Product Specific Literature References

Inhibition of platelet thromboxane synthesis by 7-(1-imidazolyl) heptanoic acid: dissociation from inhibition of aggregation: J.M. Van Nueten, et al.; J. Pharmacol. Exp. Ther. 218, 217 (1981) Abstract
[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role: J.E. Leysen, et al.; Mol. Pharmacol. 21, 301 (1982) Abstract
The pharmacology of ketanserin, the first selective serotonin S2-antagonist: F. Awouters; Drug Dev. Res. 6, 263 (1985)
Ketanserin: a novel cardiovascular drug: J. Symoens, et al.; Drug Dev. Res. 8, 159 (1986)
Ketanserin and ritanserin discriminate between recombinant human 5-HT1D alpha and 5-HT1D beta receptor subtypes: J.M. Zgombick, et al.; Eur. J. Pharmacol. 291, 9 (1995) Abstract
Differences in the effects of ketanserin and GR127935 on 5-HT-receptor mediated responses in rabbit saphenous vein and guinea-pig jugular vein: Z. Razzaque, et al.; Eur. J. Pharmacol. 283, 199 (1995) Abstract

another CS2 website

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.