ALEXIS Biochemicals: L-Quisqualic acid

ALX-550-059

Revised 23-May-06

L-Quisqualic acid
PRODUCT LINE	Neurobiology
PRODUCT CATEGORY	Glutamate Receptors (Metabotropic) / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-550-059-M005		5 mg	70.00 USD
ALX-550-059-M025		25 mg	280.00 USD

Product Specification

FORMULA:	C₅H₇N₃O₅
MW:	189.1
CAS NUMBER:	52809-07-1
MERCK INDEX:	14: 8085
PURITY:	≥99% (free from glutamate)
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in dilute aqueous base.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C

Product Description

Potent group I mGluR agonist and quis-qualate/AMPA ionotropic receptor agonist. Sensitizes neurons in hippocampus to depo-larization by L-AP6 (“quis” effect).

Product Specific Literature References

The action of natural and synthetic isomers of quisqualic acid at a well-defined glutamatergic synapse: P. Boden, et al.; Brain Res. 385, 205 (1986) Abstract
Metabotropic glutamate receptors in brain function and pathology: D.D. Schoepp and P.J. Conn; TIPS 14, 13 (1993), (Review) Abstract
Agonists and antagonists for metabotropic glutamate receptors: P.L. Ornstein, et al.; Curr. Pharm. Design 1, 355 (1995), (Review)
Pharmacological agents acting at subtypes of metabotropic glutamate receptors: D.D. Schoepp, et al.; Neuropharmacology 38, 1431 (1999), (Review) Abstract

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AMPA Receptors / Related Products

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