ALEXIS Biochemicals: Lavendustin C

ALX-270-066

Revised 07-Apr-08

Lavendustin C
SYNONYMS	Compound 5 5-(N-2,5-Dihydroxybenzyl)aminosalicylic acid
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Natural Products - Protein Kinase Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-066-M001		1 mg	35.00 USD

Product Specification

FORMULA:	C₁₄H₁₃NO₅
MW:	275.3
SOURCE/HOST:	Synthetic.
PURITY:	≥97%
APPEARANCE:	Off-white solid.
SOLUBILITY:	Soluble in DMSO or 100% ethanol.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.
HAZARD:	TOXIC.

Product Description

Potent inhibitor of protein tyrosine kinases and Ca²⁺/calmodulin-dependent kinase II. Acts also as an inhibitor of EGFR tyrosine kinase and pp60^c-src kinase.

Product Specific Literature References

Isolation of a novel tyrosine kinase inhibitor, lavendustin A, from Streptomyces griseolavendus: T. Onoda, et al.; J. Nat. Prod. 52, 1252 (1989) Abstract
Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors: T.J. O'Dell, et al.; Nature 353, 558 (1991) Abstract
Hypericin and pseudohypericin specifically inhibit protein kinase C: possible relation to their antiretroviral activity: I. Takahashi, et al.; BBRC 165, 1207 (1989) Abstract
Inhibition of crystal-induced neutrophil activation by a protein tyrosine kinase inhibitor: H.M. Burt, et al.; J. Leukoc. Biol. 55, 112 (1994) Abstract
Endotoxin increases intercellular resistance in microvascular endothelial cells by a tyrosine kinase pathway: D. Lidington, et al.; J. Cell Physiol. 185, 117 (2000) Abstract

Related Products

ALX-350-084

Lavendustin C methyl ester

Further Categories Containing This Product:

CAM Kinase Inhibitors • Tyrosine Kinase Inhibitors • EGFR Kinase Inhibitors • Lipopolysaccharides [LPS] / Related Products

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