ALEXIS Biochemicals: Levofloxacin . hydrochloride

ALX-380-292

Revised 15-Apr-08

Levofloxacin . hydrochloride
SYNONYMS	(S)-(-)-9-fluoro-2,3-dihydro-3-methyl-10- (4-methyl-1-piperazinyl)-7-oxo-7H-pyrido [1,2,3-de]-1,4-benzoxazine-6-carboxylic acid . hydrochloride S-(-)-Ofloxacin . hydrochloride

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-292-G001		1 g	30.00 USD
ALX-380-292-G005		5 g	70.00 USD

Product Specification

FORMULA:	C₁₈H₂₀FN₃O₄. HCl
MW:	361.4 . 36.5
CAS NUMBER:	177325-13-2
MERCK INDEX:	14: 6771
RTECS:	UU8815550
PURITY:	≥89.5% (Assay)
APPEARANCE:	Slightly yellow crystalline powder.
SOLUBILITY:	Soluble in water (25mg/ml).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HAZARD:	HARMFUL.

Product Description

Fluoroquinolone with broad spectrum activity against Gram-negative and Gram-positive bacteria. Active enantiomer of ofloxacin with twice its potency. Inhibits bacterial DNA-gyrase (topoisomerase).

Product Specific Literature References

Levofloxacin. A review of its antibacterial activity, pharmacokinetics and therapeutic efficacy: R. Davis & H.M: Bryson; Drugs 47, 677 (1994) Abstract
The clinical pharmacokinetics of levofloxacin: D.N. Fish & A.T. Chow; Clin. Pharmacokinet. 32, 101 (1997) Abstract
Levofloxacin: an updated review of its use in the treatment of bacterial infections: M. Hurst, et al.; Drugs 62, 2127 (2002) Abstract
Levofloxacin : a review of its use as a high-dose, short-course treatment for bacterial infection: V.R. Anderson & C.M. Perry; Drugs 68, 535 (2008) Abstract