ALEXIS Biochemicals: Lidocaine N-ethyl bromide (quaternary salt)

ALX-550-252

Revised 04-Feb-05

Lidocaine N-ethyl bromide (quaternary salt)
SYNONYMS	QX-314 N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium bromide
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Na+ Channels

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-550-252-M010		10 mg	20.00 USD
ALX-550-252-M050		50 mg	80.00 USD

Product Specification

FORMULA:	C₁₆H₂₇BrN₂O
MW:	343.3
CAS NUMBER:	21306-56-9
PURITY:	≥99%
APPEARANCE:	White solid.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C
HANDLING:	Protect from light.

Product Description

Quaternary derivative of lidocaine (Prod. No. ALX-550-251) that is not membrane permeable. Blocks both fast, Na⁺-dependent action potentials and voltage-dependent, non-inactivating Na⁺ conductance.

Product Specific Literature References

Effects of local anesthetic QX-314 on the membrane properties of hippocampal pyramidal neurons: B.W. Connors & D.A. Prince; J. Pharmacol. Exp. Ther. 220, 476 (1982) Abstract
Interactions of monovalent cations with sodium channels in squid axon. II. Modification of pharmacological inactivation gating: J.Z. Yeh & G.S. Oxford; J. Gen. Physiol. 85, 603 (1985) Abstract

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