ALEXIS Biochemicals: Lysyl Oxidase-like Protein 4 (human) (recombinant) (His)

ALX-201-258

Revised 18-Mar-08

Lysyl Oxidase-like Protein 4 (human) (recombinant) (His)
SYNONYMS	LOXL4 (human) (recombinant) (His)
PRODUCT LINE	DNA Regulation / Transcription
PRODUCT CATEGORY	Nucleic Acid Oxidation & Alkylation / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-201-258-C100		100 µg	390.00 USD

Product Specification

MW:	~65kDa
SOURCE/HOST:	Produced in E. coli. Human lysyl oxidase-like protein 4 (LOXL4) (aa 159-756) is fused to a His-tag.
CONCENTRATION:	~0.33mg/ml after reconstitution.
PURITY:	≥95% (SDS-PAGE)
FORMULATION:	Lyophilized from 50mM HEPES, pH 8.0, containing 200mM sodium chloride.
RECONSTITUTION:	Reconstitute with 300µl of 10% glycerol containing 2mM β-mercaptoethanol.
SPECIFIC ACTIVITY:	0.02-0.03µmol/min/µg
APPLICATION:	In vitro conjugation assays by monitoring benzylamine oxidation at A_250mm. Typical concentration to support conjugation in vitro is 0.5-2.5µM depending on conditions.
SHIPPING:	SHIPPED ON DRY ICE
LONG TERM STORAGE:	-80°C
HANDLING:	Avoid freeze/thaw cycles.

Product Images

Please click on thumbnails to enlarge.

Product Specific Literature References

A novel human lysyl oxidase-like gene (LOXL4) on chromosome 10q24 has an altered scavenger receptor cysteine rich domain: L. Asuncion, et al.; Matrix Biol. 20, 487 (2001) Abstract
Cloning and characterization of a fifth human lysyl oxidase isoenzyme: the third member of the lysyl oxidase-related subfamily with four scavenger receptor cysteine-rich domains: J.M. Maki, et al.; Matrix Biol. 20, 493 (2001) Abstract
Lysyl oxidases: a novel multifunctional amine oxidase family: K. Csiszar; Prog. Nucl. Acid Res. Mol. Biol. 70, 1 (2001) Abstract
Molecular cloning and biological activity of a novel lysyl oxidase-related gene expressed in cartilage: H. Ito, et al.; J. Biol. Chem. 276, 24023 (2001) Abstract; Full Text
A molecular role for lysyl oxidase in breast cancer invasion: D.A. Kirschmann, et al.; Cancer Res. 62, 4478 (2002) Abstract; Full Text
Purification of enzymatically active human lysyl oxidase and lysyl oxidase-like protein from Escherichia coli inclusion bodies: S.T. Jung, et al.; Protein Expr. Purif. 31, 240 (2003) Abstract
Expression and purification of enzymatically active forms of the human lysyl oxidase-like protein 4: M.S. Kim, et al.; J. Biol. Chem. 278, 52071 (2003) Abstract; Full Text
Structural and functional diversity of lysyl oxidase and the LOX-like proteins: J. Molnar, et al.; Biochim. Biophys. Acta 1647, 220 (2003) Abstract
Lysyl oxidase is essential for hypoxia-induced metastasis: J.T. Erler, et al.; Nature 440, 1222 (2006) Abstract
Selective upregulation and amplification of the lysyl oxidase like-4 (LOXL4) gene in head and neck squamous cell carcinoma: T. Gorogh, et al.; J. Pathol. 212, 74 (2007) Abstract
LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer: G. Wu, et al; Cancer Res. 67, 4123 (2007) Abstract

General Information

BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link Q96JB6: Lysyl Oxidase-like Protein 4 (human)

Further Categories Containing This Product:

Recombinant Proteins / Fusion Proteins

another CS2 website

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.