ALEXIS Biochemicals: MDL-12,330A . hydrochloride

ALX-270-080

Revised 17-Apr-08

MDL-12,330A . hydrochloride
SYNONYMS	cis-N-(2-Phenylcyclopentyl)azacyclotridec-1-en-2-amine . HCl
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Adenylyl Cyclase Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-080-M001		1 mg	28.00 USD
ALX-270-080-M005		5 mg	75.00 USD

Product Specification

FORMULA:	C₂₃H₃₆N₂ . HCl
MW:	340.6 . 36.5
CAS NUMBER:	40297-09-4
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in water (2.75mg/ml), 100% ethanol (>10mg/ml), DMSO (7mg/ml) or hot 0.1N HCl (0.5 mg/ml); insoluble in 0.1N NaOH. .
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C

Product Description

Cell permeable irreversible inhibitor of adenylate cyclase (IC₅₀= 250µM).

Product Specific Literature References

Actions of vasopressin and isoprenaline on the ionic transport across the isolated frog skin in the presence and the absence of adenyl cyclase inhibitors MDL12330A and SQ22536: C. Lippe & C. Ardizzone; Comp. Biochem. Physiol. 99, 209 (1991) Abstract
Tonic adenosine A2A receptor activation modulates nicotinic autoreceptor function at the rat neuromuscular junction: P. Correia-de-Sa & J.A. Ribeiro; Eur. J. Pharmacol. 271, 349 (1994) Abstract

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