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ALX-550-071 Revised 07-Mar-08
Melatonin
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SYNONYMS N-Acetyl-5-methoxytryptamine
PRODUCT LINE Neurobiology
PRODUCT CATEGORY Melatonin Receptors/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-550-071-G001   1 g 35.00 USD Add To Cart
ALX-550-071-G005   5 g 105.00 USD Add To Cart
Product Specification
FORMULA: C13H16N2O2
MW: 232.3
CAS NUMBER: 73-31-4
MERCK INDEX: 14: 5816
RTECS: AC5955000
PURITY: ≥99%
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in dilute aqueous acid or 100% ethanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HANDLING: Protect from light.

Product Specific Literature References
Physiological concentrations of melatonin inhibit nitric oxide synthase in rat cerebellum: D. Pozo, et al.; Life Sci. 55, PL455 (1994) Abstract
Melatonin receptors: are there multiple subtypes?: M.L. Dubocovich; TIPS 16, 50 (1995), (Review) Abstract
Melatonin comes of age?: R.M. Hagan & N.R. Oakley; TIPS 16, 81 (1995), (Review) Abstract
Melatonin receptors step into the light: cloning and classification of subtypes: S.M. Reppert, et al.; TIPS 17, 100 (1996), (Review) Abstract
Melatonin madness: S.M. Reppert & D.R. Weaver; Cell 83, 1059 (1995), (Minireview) Abstract
Melatonin is a scavenger of peroxynitrite: E. Gilad, et al.; Life Sci. 60, PL169 (1997) Abstract
Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin: D. Pozo, et al.; J. Cell Biochem. 65, 430 (1997) Abstract
Melatonin inhibits expression of the inducible isoform of nitric oxide synthase in murine macrophages: role of inhibition of NFkappaB activation: E. Gilad, et al.; FASEB J. 12, 685 (1998) Abstract; Full Text
Oxidative damage in the central nervous system: protection by melatonin: R.J. Reiter; Prog. Neurobiol. 56, 359 (1998) Abstract
The oxidant/antioxidant network: role of melatonin: R.J. Reiter, et al.; Biol. Signals Recept. 8, 56 (1999), (Review) Abstract
Interactions between melatonin, reactive oxygen species, and nitric oxide: D.K. Lahiri & C. Ghosh; Ann. N. Y. Acad. Sci. 893, 325 (1999) Abstract
Nitrosation of melatonin by nitric oxide and peroxynitrite: B. Blanchard, et al.; J. Pineal. Res. 29, 184 (2000) Abstract
Melatonin suppresses NO-induced apoptosis via induction of Bcl-2 expression in PGT-beta immortalized pineal cells: Y.M. Yoo, et al.; J. Pineal. Res. 33, 146 (2002) Abstract
Mitochondrial regulation by melatonin and its metabolites: D. Acuna-Castroviejo, et al.; Adv. Exp. Med. Biol. 527, 549 (2003), (Review) Abstract
Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding: W.G. Deng, et al.; Blood 108, 518 (2006) Abstract
Melatonin and nitric oxide: S. Aydogan, et al.; J. Endocrinol. Invest. 29, 281 (2006), (Review) Abstract
Melatonin inhibits endothelial nitric oxide production in vitro: E.K. Tamura, et al.; J. Pineal. Res. 41, 267 (2006) Abstract
 
 

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