ALEXIS Biochemicals: Microcystin-LW

ALX-350-080

Revised 11-Jan-08

Microcystin-LW
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Microcystins

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-080-C025		25 µg	135.00 USD
ALX-350-080-C100		100 µg	390.00 USD

Product Specification

FORMULA:	C₅₄H₇₂N₈O₁₂
MW:	1025.2
SOURCE/HOST:	Isolated from Microcystis aeruginosa.
PURITY:	≥95% (HPLC)
APPEARANCE:	Whitish film adhered to inside of the vial.
SOLUBILITY:	Soluble in 100% methanol.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	For maximum product recovery after thawing, centrifuge the vial before opening the cap.
HAZARD:	MAY BE CARCINOGENIC. HIGHLY IRRITANT. VERY TOXIC.

Product Description

Analog of microcystin-LR (Prod. No. ALX-350-012) with Trp substituted in place of Arg. Hydrophobic and believed to be more cell permeable than other microcystins. May prove useful in biochemical studies in intact cells. Microcystin-LW has a characteristically different absorption spectrum compared to other microcystins, making it a useful reference compound for HPLC analysis. The Trp confers an absorption maximum at 222nm, whereas most microcystins have a characteristic maximum at 239nm.

Product Specific Literature References

Extraction and high-performance liquid chromatographic method for the determination of microcystins in raw and treated waters: L.A. Lawton, et al.; Analyst 119, 1525 (1994) Abstract
Isolation and characterization of microcystins from laboratory cultures and environmental samples of Microcystis aeruginosa and from an associated animal toxicosis: L.A. Lawton, et al.; Nat. Toxins 3, 50 (1995) Abstract
Comparative toxicity of four microcystins of different hydrophobicities to the protozoan, Tetrahymena pyriformis: C.J. Ward & G.A. Codd; J. Appl. Microbiol. 86, 874 (1999) Abstract
Detection and quantification of microcystins (cyanobacterial hepatotoxins) with recombinant antibody fragments isolated from a naive human phage display library: J. McElhiney, et al.; FEMS Microbiol. Lett. 193, 83 (2000) Abstract

ALX-804-585	Monoclonal Antibody to Microcystins (Adda specific) (AD4G2)
ALX-850-319	Microcystins (Adda specific) ELISA Kit
ALX-350-044	Microcystin-YR
ALX-350-043	Microcystin-RR
ALX-350-148	Microcystin-LY
ALX-350-012	Microcystin-LR
ALX-350-096	Microcystin-LA
ALX-350-081	Microcystin-LF