ALEXIS Biochemicals: Monoclonal Antibody to CD49f (human) (MAR6)

ALX-804-621

Revised 03-Jan-07

Monoclonal Antibody to CD49f (human) (MAR6)
SYNONYMS	anti-α6 Integrin (human) MAb (MAR6) anti-VLA-6 (human) MAb (MAR6)
PRODUCT LINE	Immunology
PRODUCT CATEGORY	CD Antibodies

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-804-621-C100		100 µg	320.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human
CLONE:	MAR6
ISOTYPE:	Mouse IgG1
FORMULATION:	Liquid. Purified antibody containing 150mM sodium chloride and 0.02% sodium azide, pH 7.4.
IMMUNOGEN:	Recombinant human CD49f (α6 integrin).
SPECIFICITY:	Recognizes human CD49f. Detects a band of ~130kDa by IP.
APPLICATION:	Flow Cytometry Immunohistochemistry (frozen sections) Immunoprecipitation
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	+4°C
HANDLING:	Do not freeze.

Product Specific Literature References

Polarization of the alpha 6 beta 4 integrin in ovarian carcinomas: C. Bottini, et al.; Int. J. Cancer 54, 261 (1993) Abstract
Membrane vesicles shed into the extracellular medium by human breast carcinoma cells carry tumor-associated surface antigens: V. Dolo, et al.; Clin. Exp. Metastasis 13, 277 (1995) Abstract
Co-regulation and physical association of the 67-kDa monomeric laminin receptor and the alpha6beta4 integrin: E. Ardini, et al.; J. Biol. Chem. 272, 2342 (1997) Abstract
Prognostic value of alpha 6 beta 4 integrin expression in breast carcinomas is affected by laminin production from tumor cells: E. Tagliabue, et al.; Clin. Cancer Res. 4, 407 (1998) Abstract
Growth factor-dependent activation of alphavbeta3 integrin in normal epithelial cells: implications for tumor invasion: L. Trusolino, et al.; J. Cell Biol. 142, 1145 (1998) Abstract
Human hepatocellular carcinoma (HCC) cells require both alpha3beta1 integrin and matrix metalloproteinases activity for migration and invasion: G. Giannelli, et al.; Lab. Invest. 81, 613 (2001) Abstract
SEL1L expression decreases breast tumor cell aggressiveness in vivo and in vitro: R. Orlandi, et al.; Cancer Res. 62, 567 (2002) Abstract
Transforming growth factor-beta1 triggers hepatocellular carcinoma invasiveness via alpha3beta1 integrin: G. Giannelli, et al.; Am. J. Pathol. 161, 183 (2002) Abstract
Differential expression and topography of adhesion molecules in laryngeal and oropharyngeal carcinomas: E. Ricci, et al.; Acta. Otolaryngol. 122, 234 (2002) Abstract

Further Categories Containing This Product:

Monoclonal Antibodies • Adhesion Molecules & Receptors Antibodies

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