ALEXIS Biochemicals: Monoclonal Antibody to JNK/p38 (phosphorylated) (9H8)

ALX-804-241

Revised 30-May-08

Monoclonal Antibody to JNK/p38 (phosphorylated) (9H8)
SYNONYMS	anti-SAPK1/2 (phosphorylated) MAb (9H8) anti-SAP Kinase 1/2 (phosphorylated) MAb (9H8)
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	JNK [SAPK1]/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-804-241-C100		100 µg	453.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse
CLONE:	9H8
ISOTYPE:	Mouse IgG1
PURITY DETAIL:	Purified from serum-free cell culture supernatant by subsequent thiophilic adsorption and size exclusion chromatography.
FORMULATION:	Lyophilized from 1ml 2x PBS, 0.09% sodium azide, PEG and sucrose.
RECONSTITUTION:	Reconstitute with 1ml distilled water (15 min., RT).
IMMUNOGEN:	Synthetic peptide corresponding to a portion of phosphorylated JNK and p38.
SPECIFICITY:	Recognizes the TG/PpT motif of activated, monophosphorylated and the dually phosphorylated site pTG/PpT of human and mouse JNK and p38. Does not cross-react with the non-phosphorylated form of the protein or with activated ERK1 or ERK2.
APPLICATION:	Immunohistochemistry Immunoprecipitation Western Blot: Recommended blocking buffer CPPT: 10mM TRIS-HCl, pH 7.4, 0.5% (w/v) casein, 1% (w/v) PEG 4’000, 1% (w/v) polyvinylpyrrolidone, 0.1% (v/v) Tween 20, 150mM sodium chloride.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Reconstituted antibody is stable for 1 year when stored at -80°C. Thaw aliquots at +37°C. Thawed aliquots may be stored at +4°C for up to 3 months.
HANDLING:	Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and freeze in liquid nitrogen.
POSITIVE CONTROL:	Included (Prod. No. ALX-840-037).

Product Description

Stress-activated Protein Kinases (SAPKs) are strongly activated in response to adverse stimuli such as heat and osmotic shock, UV light and other DNA-damaging reagents, and inhibitors of protein synthesis. They are also activated strongly in response to agonists that are released or produced under conditions of stress, such as proinflammatory cytokines

Further Categories Containing This Product:

Phospho-specific Antibodies • p38 Kinases/Related Products • Monoclonal Antibodies

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