ALEXIS Biochemicals: Monoclonal Antibody to PIDD (Anto-1)

ALX-804-837

Revised 06-Nov-07

Monoclonal Antibody to PIDD (Anto-1)
SYNONYMS	anti-PIDD MAb (Anto-1)
PRODUCT LINE	Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY	Adaptor Proteins for Death Receptors Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-804-837-C100		100 µg	340.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse
CLONE:	Anto-1
ISOTYPE:	Mouse IgG1
SOURCE/HOST:	Purified from concentrated hybridoma tissue culture supernatant.
CONCENTRATION:	1mg/ml
PURITY:	≥95% (SDS-PAGE)
FORMULATION:	Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:	Recombinant human PIDD death domain (aa 776-910).
SPECIFICITY:	Recognizes human and mouse PIDD. Detects bands of ~90kDa (full length protein) and ~50kDa (cleaved protein) by Western blot.
APPLICATION:	Immunohistochemistry (paraffin sections) Western Blot (1:500)
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 1 year after receipt when stored at -20°C.
HANDLING:	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.

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Product Specific Literature References

Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway: A. Tinel, et al.; EMBO J. 26, 197 (2007) Abstract

General Information

MANUFACTURER

Manufactured by Apotech Corporation.

General Literature References

PIDD mediates NF-kappaB activation in response to DNA damage: S. Janssens, et al.; Cell 123, 1079 (2005) Abstract