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ALX-804-128 Revised 22-Aug-08
Monoclonal Antibody to BAFF (human) (Buffy-1)
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SYNONYMS anti-BLyS (human) MAb (Buffy-1)
anti-TALL-1 (human) MAb (Buffy-1)
anti-THANK (human) MAb (Buffy-1)
anti-zTNF4 (human) MAb (Buffy-1)
anti-TNFSF 13B/20 (human) MAb (Buffy-1)
anti-CD257 (human) MAb (Buffy-1)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY BAFF
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-128-C100   100 µg 360.00 USD Add To Cart
ALX-804-128F-T100 FITC 100 tests 380.00 USD Add To Cart
ALX-804-128TD-T100 ATTO 488 100 tests 390.00 USD Add To Cart
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Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: Buffy-1
ISOTYPE: Rat IgG2a
CONCENTRATION: 1mg/ml
PURITY: ≥95% (SDS-PAGE)
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant human soluble BAFF (aa 83-285) (Prod. No. ALX-522-025).
SPECIFICITY: Recognizes membrane-bound human BAFF. Detects endogenous protein by FC.
APPLICATION: Buffy-1:
Flow Cytometry
Immunocytochemistry
Western Blot
Buffy-1-ATTO 488:
Flow Cytometry (1:1’000)
Immunocytochemistry
Buffy-1-FITC:
Flow Cytometry
Immunocytochemistry
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
USE/STABILITY: Stable for at least 6 months after receipt when stored as recommended.
HANDLING: For long term storage keep unconjugated antibody at -20°C. Avoid freeze/thaw cycles. Keep conjugated formats at +4°C. Do not freeze. Protect from light.
POSITIVE CONTROL: For Positive Control (Western blot) see Prod. No. ALX-840-605.
Product Images
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Product Description
New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 488 shows bright green fluorescence (λabs (max): 501nm, λem (max): 523nm, εmax: 90’000).
Product Specific Literature References
BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth: P. Schneider, et al.; J. Exp. Med. 189, 1747 (1999) Abstract
BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population: J.S. Thompson, et al.; J. Exp. Med. 192, 129 (2000) Abstract; Full Text
A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth: P. Rennert, et al.; J. Exp. Med. 192, 1677 (2000) Abstract
Aberrant expression of B-lymphocyte stimulator by B chronic lymphocytic leukemia cells: a mechanism for survival: A.J. Novak, et al.; Blood 100, 2973 (2002) Abstract; Full Text
BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone: J. Moreaux, et al.; Blood 103, 3148 (2004) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION Buffy-1-FITC: 1 test means: 1µl of a 0.1mg/ml stock solution were used to stain 200’000 cells in a sample volume of 50µl.
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth: P. Schneider, et al.; J. Exp. Med. 189, 1747 (1999) Abstract
BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population: J.S. Thompson, et al.; J. Exp. Med. 192, 129 (2000) Abstract
Further Categories Containing This Product:
Monoclonal AntibodiesCD Antibodies
 
 

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