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ALX-801-029 Revised 15-Oct-07
Monoclonal Antibody to Breast Cancer Resistance Protein (human) (BXP-21)
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SYNONYMS anti-BCRP (human) MAb (BXP-21)
anti-MXR (human) MAb (BXP-21)
anti-ABCG2 (human) MAb (BXP-21)
anti-CD338 (human) MAb (BXP-21)
PRODUCT LINE Cancer
PRODUCT CATEGORY Breast Cancer Resistance Protein [BCRP / MXR] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-801-029-C125   125 µg 350.00 USD Add To Cart
ALX-801-029-C250   250 µg 630.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: BXP-21
ISOTYPE: Mouse IgG2a
CONCENTRATION: ~250µg/ml
FORMULATION: Liquid. In serum free cell culture supernatant containing 0.7% BSA and 0.1% sodium azide.
IMMUNOGEN: Recombinant human BCRP (breast cancer resistance protein; MXR) (aa 271-396).
SPECIFICITY: Recognizes an internal epitope of human BCRP. Does not cross-react with human P-glycoprotein, MRP1 or MRP2.
APPLICATION: Immunocytochemistry: Use 1:20-1:50 dilution on acetone fixed cytospin preparations.
Immunohistochemistry:
Frozen sections: Use 1:20 dilution on acetone fixed frozen sections followed by incubation with rabbit anti-mouse IgG and a monoclonal mouse APAAP complex.
Paraffin sections: Use on formaldehyde-fixed paraffin-embedded human tissues and tumors after pretreatment with 10mM citric acid, pH 6.0, for 20 min.
Western Blot
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
Product Specific Literature References
Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues: M. Maliepaard, et al.; Cancer Res. 61, 3458 (2001) Abstract; Full Text
Characterization of Drug Transport, ATP Hydrolysis, and Nucleotide Trapping by the Human ABCG2 Multidrug Transporter : C. Özvegy, et al.; J. Biol. Chem. 277, 47980 (2002) Abstract; Full Text
General Literature References
A multidrug resistance transporter from human MCF-7 breast cancer cells: L.A. Doyle, et al.; PNAS 95, 15665 (1998) Abstract; Full Text
Further Categories Containing This Product:
Monoclonal Antibodies • Tumor Markers
 
 
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