ALEXIS Biochemicals: Monoclonal Antibody to CD14 (biG 14)

ALX-804-497

Revised 08-Feb-06

Monoclonal Antibody to CD14 (biG 14)
PRODUCT LINE	Inflammation
PRODUCT CATEGORY	CD14 / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-804-497-C100		100 µg	295.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Dog Pig Others
CLONE:	biG 14
ISOTYPE:	Mouse IgG2a
CONCENTRATION:	1mg/ml after reconstitution.
PURITY DETAIL:	Protein G-affinity purified.
FORMULATION:	Lyophilized from PBS. Contains no preservatives.
RECONSTITUTION:	Reconstitute with 100µl distilled water.
IMMUNOGEN:	Monocytes of different species and immunoaffinity purified soluble human CD14.
SPECIFICITY:	Recognizes human (epitope aa 39-44), bovine, pig, dog, horse and guinea pig CD14.
APPLICATION:	ELISA Flow Cytometry Western Blot Functional Application (Inhibits binding of LPS to CD14; 1µg/ml MAb inhibits binding of 0.5µg/ml LPS to CD14).
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
HANDLING:	Avoid freeze/thaw cycles.

Product Specific Literature References

Mutation of amino acids 39-44 of human CD14 abrogates binding of lipopolysaccharide and Escherichia coli: F. Stelter, et al.; Eur J Biochem 243, 100 (1997) Abstract

General Information

The CD14 glycoprotein, gp 55, is present on most monocytic and macrophage like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for endotoxin.
BACKGROUND/TECHNICAL INFORMATION	Binding titer at human CD14 transfected CHO-cells is more than 10'000.
MANUFACTURER	Manufactured by Biometec.

Further Categories Containing This Product:

CD Antibodies • Monoclonal Antibodies

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