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ALX-803-314 Revised 10-Apr-08
Monoclonal Antibody to COMP (484D1)
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SYNONYMS anti-Cartilage Oligomeric Matrix Protein MAb (484D1)
PRODUCT LINE Cytoskeleton
PRODUCT CATEGORY Cytoskeleton & Extracellular Matrix Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-803-314-R100   100 µl 310.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Rat
Others
CLONE: 484D1
ISOTYPE: Rat IgG1
FORMULATION: Liquid. Ascites.
IMMUNOGEN: Human COMP (cartilage oligomeric matrix protein).
SPECIFICITY: Recognizes human, rat and bovine COMP.
APPLICATION: ELISA (1:500-1:2'000)
Immunohistochemistry (frozen sections (1:100-1:300))
Immunoprecipitation (1:100-1:300)
Western Blot (1:100-1:1'000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Expression of cartilage oligomeric matrix protein (COMP) by embryonic and adult osteoblasts: P.E. Di Cesare, et al.; J. Orthop. Res. 18, 713 (2000) Abstract
Matrix-matrix interaction of cartilage oligomeric matrix protein and fibronectin: P.E. Di Cesare, et al.; Matrix Biol. 21, 461 (2002) Abstract
General Information
COMP (cartilage oligomeric matrix protein is a tissue-specific non-collagenous protein that was shown to be an important biomarker for inflammatory diseases. Mutations in the gene encoding COMP cause two common skeletal dysplasias, pseudoachondroplasia (PSACH) and mutiple epiphyseal dysplasia (MED).
General Literature References
Characterization of human and mouse cartilage oligomeric matrix protein: G. Newton, et al.; Genomics 24, 435 (1994) Abstract
Cartilage oligomeric matrix protein level in rheumatic diseases: potential use as a marker for measuring articular cartilage damage and/or the therapeutic efficacy of treatments: G. Morozzi, et al.; Ann. N.Y. Acad. Sci. 1108, 398 (2007) Abstract
Further Categories Containing This Product:
Bone Metabolism Other Products • Monoclonal Antibodies
 
 
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