ALEXIS Biochemicals: Monoclonal Antibody to Hepatitis C Core Protein (C7-50)

ALX-804-277

Revised 14-Dec-06

Monoclonal Antibody to Hepatitis C Core Protein (C7-50)
PRODUCT LINE	Viral Signalling
PRODUCT CATEGORY	Hepatitis Viruses / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-804-277-C100		100 µg	379.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Others
CLONE:	C7-50
ISOTYPE:	Mouse IgG1
CONCENTRATION:	1mg/ml
FORMULATION:	Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN:	Purified HCV (hepatitis C virus) core fusion protein (genotype 1b).
SPECIFICITY:	Recognizes epitope between aa 21-40 of HCV core protein. This sequence is conserved among different HCV strains. Detects a band of ~21kDa by Western blot.
APPLICATION:	ELISA Immunocytochemistry Immunoprecipitation Western Blot (1µg/ml)
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
HANDLING:	Avoid freeze/thaw cycles.

Product Specific Literature References

Characterization of three novel monoclonal antibodies against hepatitis C virus core protein: D. Moradpour, et al.; J. Med. Virol. 48, 234 (1996) Abstract

General Information

Hepatitis C virus (HCV) is the primary cause of non-A, non-B hepatitis and results in most HCV-infected people developing chronic infections, liver cirrhosis and hepatocellular carcinoma. The 21kDa core protein of HCV is well conserved among different HCV genotypes and may suppress hepatitis B virus replication in a phosphorylation dependent manner.
BACKGROUND/TECHNICAL INFORMATION	Immunocytochemical staining of HCV core protein in transfected chimp hepatocytes yields a staining pattern consistent with cytoplasmic and vesicular staining.

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Monoclonal Antibodies

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