ALEXIS Biochemicals: Monoclonal Antibody to IKKβ (human) (10AG2)

ALX-804-237

Revised 27-Feb-07

Monoclonal Antibody to IKKβ (human) (10AG2)
SYNONYMS	anti-Inhibitor of Nuclear Factor κ-B Kinase β (human) MAb (10AG2) anti-IKK2 (human) MAb (10AG2)
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	IkB Kinases [IKKs]/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-804-237-C100		100 µg	293.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human
CLONE:	10AG2
ISOTYPE:	Mouse IgG1
CONCENTRATION:	0.5mg/ml
PURITY DETAIL:	Protein G affinity-purified.
FORMULATION:	Liquid. In PBS containing 0.2% gelatin and 0.05% sodium azide.
IMMUNOGEN:	Recombinant human IKKβ (inhibitor of NF-κB kinase β; IKK2).
SPECIFICITY:	Recognizes human IKKβ. Detects a band of ~87kDa by Western blot.
APPLICATION:	Western Blot (2-4µg/ml)
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for 6 months when stored at +4°C.

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Product Specific Literature References

Methotrexate suppresses NF-kappaB activation through inhibition of IkappaBalpha phosphorylation and degradation: S. Majumdar & B.B. Aggarwal; J. Immunol. 167, 2911 (2001) Abstract; Full Text
Thalidomide suppresses NF-kappa B activation induced by TNF and H2O2, but not that activated by ceramide, lipopolysaccharides, or phorbol ester: S. Majumdar, et al.; J. Immunol. 168, 2644 (2002) Abstract; Full Text
Impaired NF-kappa B activation and increased production of tumor necrosis factor alpha in transgenic mice expressing keratin K10 in the basal layer of the epidermis: M. Santos, et al.; J. Biol. Chem. 278, 14322 (2003) Abstract

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Monoclonal Antibodies

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