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ALX-804-818 Revised 01-Mar-07
Monoclonal Antibody to NALP3 (human) (Nalpy3-a)
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SYNONYMS anti-NACHT-, LRR- and PYD-containing Protein 3 (human) MAb (Nalpy3-a)
anti-Cryopyrin (human) MAb (Nalpy3-a)
anti-Cold Autoinflammatory Syndrome 1 Protein (human) MAb (Nalpy3-a)
anti-PYPAF1 (human) MAb (Nalpy3-a)
anti-PYRIN-containing APAF1-like Protein 1 (human) MAb (Nalpy3-a)
anti-CIAS1 (human) MAb (Nalpy3-a)
PRODUCT LINE Inflammation
PRODUCT CATEGORY Inflammasome
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-818-C100   100 µg 320.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: Nalpy3-a
ISOTYPE: Mouse IgG1
SOURCE/HOST: Purified from concentrated hybridoma tissue culture supernatant.
CONCENTRATION: 1mg/ml
PURITY: ≥95% (SDS-PAGE)
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant human NALP3 (NACHT-, LRR- and PYD-containing protein 3) (pyrin domain).
SPECIFICITY: Recognizes human NALP3. Detects endogenous protein by ICC and WB.
APPLICATION: Immunocytochemistry (1:100)
Western Blot (1:1’000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year after receipt when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles.
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Product Specific Literature References
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder: L. Agostini, et al.; Immunity 20, 319 (2004) Abstract
General Information
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation: M. Chamaillard, et al.; Cell. Microbiol. 5, 581 (2003) Abstract; Full Text
Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties: W. O'Connor, Jr., et al.; J. Immunol. 171, 6329 (2003) Abstract
Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases: F. Martinon and J. Tschopp; Cell 117, 561 (2004) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 

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