ALEXIS Biochemicals: Monoclonal Antibody to RANK (human) (9A725)

ALX-804-212

Revised 17-Sep-07

Monoclonal Antibody to RANK (human) (9A725)
SYNONYMS	anti-TRANCE-R (human) MAb (9A725) anti-ODFR (human) MAb (9A725) anti-TNFRSF 11A (human) MAb (9A725) anti-CD265 (human) MAb (9A725)
PRODUCT LINE	Chemokines & Cytokines
PRODUCT CATEGORY	RANK & RANKL

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-804-212-C100		100 µg	293.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human
CLONE:	9A725
ISOTYPE:	Mouse IgG1
CONCENTRATION:	0.5mg/ml
PURITY DETAIL:	Protein G-affinity purified.
FORMULATION:	Liquid. In PBS containing 0.2% gelatin and 0.05% sodium azide.
IMMUNOGEN:	Recombinant human RANK (aa 326-616).
SPECIFICITY:	Recognizes an epitope between aa 330-427 of human RANK. Detects a band of ~97kDa by Western blot.
APPLICATION:	Flow Cytometry (intracellular) (see [1]) Immunohistochemistry (paraffin sections) Western Blot (1-2µg/ml)
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for 6 months when stored at +4°C.

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Product Specific Literature References

[1] Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines: P. Fiumara, et al.; Blood 98, 2784 (2001) Abstract; Full Text
[2] A novel in vivo role for osteoprotegerin ligand in activation of monocyte effector function and inflammatory response: D. Seshasayee, et al.; J. Biol. Chem. 279, 30202 (2004) Abstract
[3] Evidence that receptor activator of nuclear factor (NF)-kappaB ligand can suppress cell proliferation and induce apoptosis through activation of a NF-kappaB-independent and TRAF6-dependent mechanism: A.C. Bharti, et al.; J. Biol. Chem. 279, 6065 (2004) Abstract; Full Text

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CD Antibodies • Monoclonal Antibodies

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