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ALX-804-299 Revised 24-Jun-08
Monoclonal Antibody to TRAIL-R4 (human) (HS402)
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SYNONYMS anti-DcR2 (human) MAb (HS402)
anti-TRUNDD (human) MAb (HS402)
anti-TNFRSF 10D (human) MAb (HS402)
anti-CD264 (human) MAb (HS402)
PRODUCT LINE Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY TRAIL-R4
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-299A-C100   100 µg 330.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: HS402
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml
PURITY: ≥95% (SDS-PAGE)
FORMULATION: Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN: Recombinant human TRAIL-R4 (DcR2).
SPECIFICITY: Recognizes human TRAIL-R4. Does not cross-react with human TRAIL-R1, -R2 or -R3.
APPLICATION: Flow Cytometry
Immunocytochemistry
Immunohistochemistry (frozen sections)
Immunoprecipitation.
See also anti-TRAIL Receptor-1 to -4 Flow Cytometry Set (Prod. No. ALX-850-273).
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
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Product Specific Literature References
TNF-Related Apoptosis-Inducing Ligand Mediates Tumoricidal Activity of Human Monocytes Stimulated by Newcastle Disease Virus: B. Washburn, et al.; J. Immunol. 170, 1814 (2003) Abstract
TRAIL regulates normal erythroid maturation through an ERK-dependent pathway: P. Secchiero, et al.; Blood 103, 517 (2004) Abstract
Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs: T.M. Ganten, et al.; Cell Death Differ. 11 Suppl 1, S86 (2004) Abstract
cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes: T. Wachter, et al.; J. Biol. Chem. 279, 52824 (2004) Abstract; Full Text
Resistance to FasL and tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in Sezary syndrome T-cells associated with impaired death receptor and FLICE-inhibitory protein expression: E. Contassot, et al.; Blood 111, 4780 (2008) Abstract
Related Products
Further Categories Containing This Product:
CD Antibodies • Monoclonal Antibodies
 
 
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