ALEXIS Biochemicals: Monoclonal Antibody to VE-cadherin (human) (BV6)

ALX-803-305

Revised 12-May-06

Monoclonal Antibody to VE-cadherin (human) (BV6)
PRODUCT LINE	Cytoskeleton
PRODUCT CATEGORY	Cadherin Antibodies

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-803-305-C100		100 µg	240.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human
CLONE:	BV6
ISOTYPE:	Mouse IgG2a
CONCENTRATION:	0.2mg/ml
PURITY:	Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
PURITY DETAIL:	Affinity purified.
IMMUNOGEN:	Human endothelial cells.
SPECIFICITY:	Recognizes human VE-cadherin. Does not cross-react with other species. Detects a band of ~130-140kDa by Western blot.
APPLICATION:	ELISA Flow Cytometry Immunocytochemistry (fluorescence and peroxidase staining) Immunohistochemistry (frozen section) Immunoprecipitation Western Blot (non-reducing)
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
HANDLING:	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.

Product Specific Literature References

Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin: F. Breviario, et al.; Arterioscler. Thromb. Vasc. Biol. 15, 1229 (1995) Abstract
Catenin-dependent and -independent functions of vascular endothelial cadherin: P. Navarro, et al.; J. Biol. Chem. 270, 30965 (1995) Abstract; Full Text
Inhibition of cultured cell growth by vascular endothelial cadherin (cadherin-5/VE-cadherin): L. Caveda, et al.; J. Clin. Invest. 98, 886 (1996) Abstract; Full Text
Differential localization of VE- and N-cadherins in human endothelial cells: VE-cadherin competes with N-cadherin for junctional localization: P. Navarro, et al.; J. Cell Biol. 140, 1475 (1998) Abstract; Full Text
Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization: T. Murohara, et al.; J. Clin. Invest. 105, 1527 (2000) Abstract; Full Text
Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability: M. Corada, et al.; Blood 97, 1679 (2001) Abstract; Full Text
VEGFR-3 and CD133 identify a population of CD34+ lymphatic/vascular endothelial precursor cells: P. Salven, et al.; Blood 101, 168 (2003) Abstract; Full Text
Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells: K. Xiao, et al.; J. Cell Biol. 163, 535 (2003) Abstract; Full Text
p120-Catenin regulates clathrin-dependent endocytosis of VE-cadherin: K. Xiao, et al.; Mol. Biol. Cell 16, 5141 (2005) Abstract; Full Text

Further Categories Containing This Product:

Angiogenesis Other Products • Angiogenesis Other Products • Monoclonal Antibodies

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