ALEXIS Biochemicals: Monoclonal Antibody to Viable Rat beta Cells and RIN Cells (K14D10)

ALX-803-052

Revised 07-Mar-06

Monoclonal Antibody to Viable Rat beta Cells and RIN Cells (K14D10)
PRODUCT LINE	Obesity & Adipokines
PRODUCT CATEGORY	Insulin & Insulin Receptor/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-803-052-C100		100 µg	547.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Rat
CLONE:	K14D10
ISOTYPE:	Mouse IgG2a
CONCENTRATION:	0.5mg/ml
PURITY DETAIL:	Ammonium sulphate precipitation.
FORMULATION:	Liquid. In PBS, pH 7.4, containing 0.9mg/ml sodium azide.
IMMUNOGEN:	Pig proinsulin.
SPECIFICITY:	Recognizes surface structure of viable isolated rat beta cells. Does not recognize mouse islet beta cells. Cross-reactivity with human pancreatic beta cells was not detected.
APPLICATION:	Flow Cytometry Immunohistochemistry (frozen sections) Note: Not recommended for WB and IP.
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 1 year when stored at +4°C.
HANDLING:	Avoid freeze/thaw cycles.

Product Specific Literature References

Influence of target cell preparation on binding of monoclonal islet cell reactive antibodies (mc-ICRA) in cellular enzyme-linked immunosorbent assay (CELISA): M. Schlosser, et al.; J. Immunol. Methods 140, 101 (1991) Abstract
Monoclonal antibody-mediated cytotoxicity against rat beta cells detected in vitro does not cause beta-cell destruction in vivo: B. Ziegler, et al.; Diabetologia 35, 608 (1992) Abstract
Co-culture of pancreatic islets and allogeneic lymphocytes: alterations of responder and stimulator cells: B. Kuttler, et al.; Transplantation 64, 480 (1997) Abstract
Recognition of islet-directed peripheral blood lymphocytes in vitro before rejection of allogeneic grafted islets: B. Kuttler, et al.; Transplantation 69, 1987 (2000) Abstract
Immunomagnetic purification of beta cells from rat islets of Langerhans: V. Hadjivassiliou, et al.; Diabetologia 43, 1170 (2000) Abstract

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